Aminoglycosides include:
1. Those that are derived from the genus of bacteria namely "Streptomyces". These aminoglycoside antibiotics end with "-mycin" and include:
a. Streptomycin ·
b. Neomycinc.
c. Kanamycin
d. Hygromycin B ·
e. Spectinomycin.
2. Those that are derived from the genus of bacteria namely "Micromonospora". These aminoglycoside antibiotics end with "-micin" and include:
a. Gentamicin
b. Verdamicin
3. Those that are derived from these antibiotics:
a. Arbekacin(1)
b. Framycetin
c. Amikacin
d. Paromomycin
e. Ribostamycin
f. Dibekacin
g. Tobramycin
h. Netilmicin
i. Sisomicin
j. Isepamicin(2)
k. Habekacin (N. Tanaka et al.)
Further reading:
Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery by Dey P. Arya.
References:
(1) Arti Kapil, Rashi Bali, B. K. Das, In vitro susceptibility of nosocomial isolates against a new aminoglycoside isepamicin. Indian Journal of Medical Research, Feb 2001.
(2) M. Inoue, M. Nonoyama , R. Okamoto, T. Ida. Antimicrobial activity of arbekacin, a new aminoglycoside antibiotic, against methicillin-resistant Staphylococcus aureus. Drugs under experimental and clinical research, 1994, volume 20, number 6, pages 233-239.
N. Tanaka, K. Matsunaga, A. Hirata, Y. Matsuhisa and T. Nishimura. Mechanism of action of habekacin, a novel amino acid-containing aminoglycoside antibiotic. Antimicrob Agents Chemother. 1983 November; 24(5): Pages 797–802.
Further Reading:
The Goodman and Gilman Manual of Pharmacology and Therapeutics by Laurence Brunton, Donald blumenthal, Iain buxton and Keith Parker
AHFS Drug Information 2008 (Ahfs Drug Information) by American Society of Health-system
Lippincott's Illustrated Reviews: Pharmacology, 4th Edition (Lippincott's Illustrated Reviews Series) by Richard A. Harvey, Pamela C. Champe, Richard Finkel, Luigi Cubeddu and Michelle A. Clarke
Copyright, (c), 2008, http://jeepakistan.blogspot.com
Saturday, October 11, 2008
Cocaine
Cocaine is natural alkaloid and obtaine from Coca leaves. It is used topically as local anesthetic.
Copyright (c), 2008, http://jeepakistan.blogspot.com
Friday, October 3, 2008
Warfarin
Warfarin is an oral anti-coagulant.
P. Peterson et al. had found that anticoagulation therapy with warfarin to prevent thromboembolic complications is effective.
References:
Petersen P, Boysen G, Godtfredsen J, Andersen ED, Andersen B. Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study. Lancet. 1989 Jan 28;1(8631):Pages 175-9.
Copyright (c), 2008, http://jeepakistan.blogspot.com/
P. Peterson et al. had found that anticoagulation therapy with warfarin to prevent thromboembolic complications is effective.
References:
Petersen P, Boysen G, Godtfredsen J, Andersen ED, Andersen B. Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study. Lancet. 1989 Jan 28;1(8631):Pages 175-9.
Copyright (c), 2008, http://jeepakistan.blogspot.com/
Sunday, September 21, 2008
Thyroid agents and Anti-thyroid drugs
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