P. Peterson et al. had found that anticoagulation therapy with warfarin to prevent thromboembolic complications is effective.
References:
Petersen P, Boysen G, Godtfredsen J, Andersen ED, Andersen B. Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study. Lancet. 1989 Jan 28;1(8631):Pages 175-9.
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