Saturday, April 30, 2011

Quinapril Hydrochloride



Credit: pfizer.com
It is an ethyl ester of non-sulfhydryl compound, quinaprilat.

Mechanism of Action:
It is an angiotensin converting enzyme inhibitor (ACE) inhibitor. ACE is an enzyme that converts the angiotensin-I to angiotensin-II.

Pharmacokinetics:
Peak plasma concentration of quinapril hydrochloride is found within 1 hour after administration. The extent of absorption is about 60%.

After absorption about 38% of quinapril is converted into its major active metabolite i.e. quinaprilat. About 97% of quinapril or quinaprilat is bound to plasma proteins.
Uses:
It is used in hypertension and congestive heart failure.

Contraindications:
ACE inhibitors are contraindicated in second and third trimester of pregnancy as they may cause injury and sometimes death of the developing fetus.

Brand Name:
Accupril
Accuretic (Quinapril Hydrochloride and hydrochlorothiazide)

Thursday, April 28, 2011

Job Opportunities in Pharmacies

Career Links

Co-operative Group:
http://www.co-operative.jobs/

Alliance Boots:
http://hr.allianceboots.com/hr/front/do/frontHome.do?locale=en_GB_ab

Pharmasave Canada:
http://www.pharmasave.com/default/0/careers.aspx

Lloyds Pharmacy:
http://www.lloydspharmacy.com/wps/portal/!ut/p/c1/04_SB8K8xLLM9MSSzPy8xBz9CP0os3jPgCBvSydDRwMLLw9zAyMfA1MzR-8QI5MgQ_1wkA6zeD9_o1A3E09DQwszV0MDIzMPEyefME8DdxdjiLwBDuBooO_nkZ-bql-QnZ3m6KioCABaWO5P/dl2/d1/L2dJQSEvUUt3QS9ZQnB3LzZfSVBSSzlCMUEwOEpINzAyTDA1NkFLVDI4OTM!/

Walgreens Pharmacy:
http://careers.walgreens.com/?foot=careers

Superdrug, UK:
http://www.jobpartners.com/jpapps/superdrug/

CVS Pharmacy:
http://info.cvscaremark.com/careers

Job Opportunities in Schools and Colleges of Pharmacy

Career Links

University of Wisconsin Madison, School of Pharmacy:
http://pharmacy.wisc.edu/about-school/employment-opportunities

Career site for Monash University, Victorian College of Pharmacy: http://www.pharm.monash.edu.au/students/undergrad/employment.html

Job Board of University of Arizona:

http://www.pharmacy.arizona.edu/alumni-donors/job-board

Find option in Loma Linda University, Health sciences, America:

https://www.healthcaresource.com/lomalinda/index.cfm?fuseaction=search.categoryList&template=dsp_job_categories.cfm&CFID=5499355&CFTOKEN=aeaec6b4bfaee612-F76BAFF1-15C5-ED8E-75C7D53B3D14E0AA&jsessionid=d830df5bd27c3c6c763e

In VCU School of Pharmacy:

http://www.pharmacy.vcu.edu/sub/research/careers.aspx