Tuesday, March 22, 2011

Dirithromycin

It is a macrolide antibiotic.

Mechanism of Action:
It binds to the 50S ribosomal subunit of bacteria resulting in the inhibition of the translocation of the peptides.

Uses:
It is used to treat bacterial infections such as tonsillitis, bronchitis and pneumonia.

Erythromycin

It is a macrolide antibiotic.

Mechanism of Action:
It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.

Uses:
It is used for the treatment of respiratory tract infections and pertussis.

Clarithromycin

It is a Macrolide antibiotic derived from erythromycin.

Mechanism of Action:
It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.

Uses:It is used for the treatment of acute otitis media and infections caused by H. influenzae and S. pneumoniae.

Azithromycin

It is a macrolide antibiotic.

Action:
It binds to 50S ribosomal subunit of bacterial ribosome resulting in the inhibition of the peptidyl transferase activity.

Uses:
It is used for the infections caused by H. Influenzae, C. Pneumoniae and S. aureus.

Vertilmicin

It is an aminoglycoside antibiotic. It is structurally very similar to netilmicin.

Uses:It is a potent bactericidal agent against E. coli, S. aureus and Klebsiella pneumoniae.

Tobramycin

It is an aminoglycoside antibiotic.

Action:
It binds to 30S ribosomal subunit inhibiting bacterial protein synthesis.

Used:
It is used in the treatment of infections caused by gram negative bacteria especially pseudomonas species.

Sisomicin

It is an aminoglycoside antibiotic derived from "Micromonospora" bacteria. It is closely related to gentamicin.

Uses:It is used in the treatment of the infections caused by Serratia and indole positive Proteus species.