PHARMACEUTICAL CHEMISTRY-IV (Instrumentation)
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
1. CHROMATOGRAPHIC METHODS: Column Chromatography, Thin Layer Chromatography, Gas Liquid Chromatography, HPLC and GCMS.
2. ELECTRO CHEMICAL METHODS: Potentiometry, Polarography and Radiochemical Techniques.
3. DIFFERENTIAL SCANNING CALORIMETRY.
PHARMACEUTICAL CHEMISTRY-IV (Instrumentation)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the requirements, e.g. Determination of the Purity and Composition of the unknown drugs by using at least each of the above techniques.
Recommended Books
1. Lough W J, High Performance Liquid Chromatography, Blacki Academic Press, New York, 1996
2. William Kemp,Organic Spectroscopy, Ellsi Horwood, London, 1990. 3. M Aminuddin & Javed Iqbal, Theory and Practice of Chromatography, University Grants Commission, Islamabad-Pakistan (2000).
4. A H Beckett and J B Stennlake, Practical Pharmaceutical Chemistry, Part I and II, the aulton Press, London.
5. A M Knevel and F E Digangi, Jenkins’s quantitative Pharmaceutical Chemistry, McGraw-Hill Book Company, New York.
6. A Braithwaite and F J Smith, Chromatographic Methods, Chapman and Hall, London.
7. E Heftmann, Chromatography, Von Nostrond Reinheld Co, New York, 1975.
8. A Pryde and M J Gilbert, Applications of High Performance Liquid Chromatography, Chapman & Hall, London, 1979.
9. E Stahl, Thin Layer Chromatography, Springer-Verlag, Berlin, 1969.
10. R Hamilton, Introduction to HPLC, P A Sewell, Chapman & Hall, London, 1982.
Thursday, March 3, 2011
Third Professional, Second Semester, Pharmacognosy
PHARMACOGNOSY-IV
(Theory)
Cr. Hr. 03
1. VOLATILE OILS (ESSENTIAL OILS): Introduction, significance, methods of obtaining volatile oils, chemistry and classification of:
(a) Hydrocarbon volatile oils: Cubeb and Terpentine oil.
(b) Alcoholic volatile oils: Peppermint, Coriander and Cardamom.
(c) Aldehydic volatile oils: Bitter orange peel, sweet orange peel, lemon, cinnamon and bitter almond oil.
(d) Ketonic volatile oils: Camphor, spearmint, caraway, Buchu.
(e) Phenolic volatile oils: Clove, Thyme.
(f) Phenolic ether volatile oils: Fennel, Anise, Myristica.
(g) Oxide volatile oils: Eucalyptus, chenopodium.
(h) Ester volatile oils: Rosemary.
(i) Miscellaneous volatile oils: Allium, Anethum.
2. RESINS AND RESIN COMBINATION: Introduction, properties and difference between glycoresins, oleoresins, oleo-gum resins and balsams.
(a) Resins: Rosin, Cannabis.
(b) Glycoresins: Podophyllum, Jalap, Ipomoea, Colocynth.
(c) Oleoresins: Terpentine, Capsicum, Ginger.
(d) Oleo-gum resins: Asafoetida, Myrrh.
(e) Balsams: Storax, Peruvian balsam, Tolu balsam, Benzoin.
3. ALKALOIDS: Introduction, Properties, Cassification, Function of alkaloids in plants, Methods of extraction and identification tests.
(a) Pyridine — Piperidine Alkaloids: Areca nut, Lobelia, Tobacco.
(b) Tropane Alkaloids: Belladonna, Hyoscyamus, Stramonium.
(c) Quinoline Alkaloids: Cinchona.
(d) Isoquinoline Alkaloids: Ipecacuanha, Opium.
(e) Indole alkaloids: Rauwolfia, catharanthus, nux vomica, physostigma, ergot.
(f) Imidazole alkaloids: Pilocarpus.
(g) Steroidal alkaloids: Veratrum.
(h) Alkaloidal amines: Ephedra, colchicum.
(i) Purine Bases: Tea, Coffee.
4. TUMOUR INHIBITORS FROM PLANT: Detailed study of various antitumour agents isolated from plants.
PHARMACOGNOSY-IV
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Isolation and separation of active constituents of crude drugs by paper and thin layer chromatography.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed., Lea and Febiger, Philadelphia, 1988.
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto, 2002.
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission Monograph Series, Islamabad, pp74, 1985.
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission, Islamabad, 1985.
8. Youngkin H W, Text Book of Pharmacognosy, The Blakiston Co, Toronto, 6th Ed., 1948.
(Theory)
Cr. Hr. 03
1. VOLATILE OILS (ESSENTIAL OILS): Introduction, significance, methods of obtaining volatile oils, chemistry and classification of:
(a) Hydrocarbon volatile oils: Cubeb and Terpentine oil.
(b) Alcoholic volatile oils: Peppermint, Coriander and Cardamom.
(c) Aldehydic volatile oils: Bitter orange peel, sweet orange peel, lemon, cinnamon and bitter almond oil.
(d) Ketonic volatile oils: Camphor, spearmint, caraway, Buchu.
(e) Phenolic volatile oils: Clove, Thyme.
(f) Phenolic ether volatile oils: Fennel, Anise, Myristica.
(g) Oxide volatile oils: Eucalyptus, chenopodium.
(h) Ester volatile oils: Rosemary.
(i) Miscellaneous volatile oils: Allium, Anethum.
2. RESINS AND RESIN COMBINATION: Introduction, properties and difference between glycoresins, oleoresins, oleo-gum resins and balsams.
(a) Resins: Rosin, Cannabis.
(b) Glycoresins: Podophyllum, Jalap, Ipomoea, Colocynth.
(c) Oleoresins: Terpentine, Capsicum, Ginger.
(d) Oleo-gum resins: Asafoetida, Myrrh.
(e) Balsams: Storax, Peruvian balsam, Tolu balsam, Benzoin.
3. ALKALOIDS: Introduction, Properties, Cassification, Function of alkaloids in plants, Methods of extraction and identification tests.
(a) Pyridine — Piperidine Alkaloids: Areca nut, Lobelia, Tobacco.
(b) Tropane Alkaloids: Belladonna, Hyoscyamus, Stramonium.
(c) Quinoline Alkaloids: Cinchona.
(d) Isoquinoline Alkaloids: Ipecacuanha, Opium.
(e) Indole alkaloids: Rauwolfia, catharanthus, nux vomica, physostigma, ergot.
(f) Imidazole alkaloids: Pilocarpus.
(g) Steroidal alkaloids: Veratrum.
(h) Alkaloidal amines: Ephedra, colchicum.
(i) Purine Bases: Tea, Coffee.
4. TUMOUR INHIBITORS FROM PLANT: Detailed study of various antitumour agents isolated from plants.
PHARMACOGNOSY-IV
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Isolation and separation of active constituents of crude drugs by paper and thin layer chromatography.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed., Lea and Febiger, Philadelphia, 1988.
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto, 2002.
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission Monograph Series, Islamabad, pp74, 1985.
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission, Islamabad, 1985.
8. Youngkin H W, Text Book of Pharmacognosy, The Blakiston Co, Toronto, 6th Ed., 1948.
Third Professional, Second Semester, Pharmacology
PHARMACOLOGY AND THERAPEUTICS-IV (Systemic Pharmacology-II)
(Theory)
Cr. Hr. 03
1. CHEMOTHERAPY
(a) Classification of drugs.
(b) Antimicrobials: Sulphonamides, Antivirals, Antiprotozoals (Treatment of Malaria and Treatment of Amebiasis), Antifungals, Anthelmintics, Anti-neoplastic and Immunosuppressive drugs, Drug treatment of Leprosy and Antibiotics (Penicillins, Cephalosporins, Aminoglycosides, Tetracyclines, Chloramphenicol, Macrolides, Quinolones and Miscellaneous Antibiotics).
(c) Antihypertensive Drugs.
(d) Steroids and Antisteroid drugs.
2. HORMONES, ANTAGONISTS AND OTHER AGENTS AFFECTING ENDOCRINE FUNCTION
(a) Endocrine function and dysfunctions.
(b) Drug used for therapy of Diabetes Mellitus: Insulins and Oral Hypoglycemic agents.
(c) Corticosteroids.
(d) Thyroid hormone and anti-thyroid drugs.
3. TOXICOLOGY
(a) Pollution and its typers (water, air, food).
(b) Poison and principle of treatment of poisoning.
(c) Poisoning (Sign & symptom and treatment): Ethanol, Barbiturates, Digitalis, Salicylides, Strychnine, Narcotics, Nicotine, Paracetamol, Benzodiazepines and Organophosphorous compounds.
(d) Chelating agents and their role in poisoning: Dimercaprol, Calcium disodium edentate, Pencillamine and Defroxamine.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY & THERAPEUTICS-IV (Systemic Pharmacology-II)
(Laboratory)
Cr. Hr. 01
NOTE: - Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g.
1. To identify and differentiate the effects of unknown drug on human and the nerve plexus of frog.
2. To demonstrate the effects of Acetylcholine on the Rectus abdominus muscle of frog and competitive.
3. Pharmacological antagomism by Neuromuscular blocking agent e.g. Gallamine.
4. To identify the unknown drug by performing pharmacological competitive antagonism on Rectus.
5. Abdominus muscle of Frog.
6. To study the anti-coagulant effects of Heparin and oral anti-coagulants on Rabbits.
7. To identify the unknown anti-coagulant drug using Rabbits.
8. To demonstrate the graded Dose-Response curve of Acetylcholine on Rabbit intestine.
9. To identify unknown concentration of Acetycholine from graded Dose- Response curves.
Recommended Books (Pharmacology)
1. Goodman Gillman, Pharmacological basis of therapeutics.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology,
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics,
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi,
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung, B G, Basic and Clinical Pharmacology,
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001.
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993.
10. Qayum A Fundamentals of Experimental Pharmacology.
11. Bertram G K, Basic and Clinical Pharmacology, Paramount Publishing Business & Professional Group, USA, 6th Ed., 1995.
12. William F Ganong, W F, Review of Medical physiology, Prentice Hall International Inc, New Jersey.
(Theory)
Cr. Hr. 03
1. CHEMOTHERAPY
(a) Classification of drugs.
(b) Antimicrobials: Sulphonamides, Antivirals, Antiprotozoals (Treatment of Malaria and Treatment of Amebiasis), Antifungals, Anthelmintics, Anti-neoplastic and Immunosuppressive drugs, Drug treatment of Leprosy and Antibiotics (Penicillins, Cephalosporins, Aminoglycosides, Tetracyclines, Chloramphenicol, Macrolides, Quinolones and Miscellaneous Antibiotics).
(c) Antihypertensive Drugs.
(d) Steroids and Antisteroid drugs.
2. HORMONES, ANTAGONISTS AND OTHER AGENTS AFFECTING ENDOCRINE FUNCTION
(a) Endocrine function and dysfunctions.
(b) Drug used for therapy of Diabetes Mellitus: Insulins and Oral Hypoglycemic agents.
(c) Corticosteroids.
(d) Thyroid hormone and anti-thyroid drugs.
3. TOXICOLOGY
(a) Pollution and its typers (water, air, food).
(b) Poison and principle of treatment of poisoning.
(c) Poisoning (Sign & symptom and treatment): Ethanol, Barbiturates, Digitalis, Salicylides, Strychnine, Narcotics, Nicotine, Paracetamol, Benzodiazepines and Organophosphorous compounds.
(d) Chelating agents and their role in poisoning: Dimercaprol, Calcium disodium edentate, Pencillamine and Defroxamine.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY & THERAPEUTICS-IV (Systemic Pharmacology-II)
(Laboratory)
Cr. Hr. 01
NOTE: - Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g.
1. To identify and differentiate the effects of unknown drug on human and the nerve plexus of frog.
2. To demonstrate the effects of Acetylcholine on the Rectus abdominus muscle of frog and competitive.
3. Pharmacological antagomism by Neuromuscular blocking agent e.g. Gallamine.
4. To identify the unknown drug by performing pharmacological competitive antagonism on Rectus.
5. Abdominus muscle of Frog.
6. To study the anti-coagulant effects of Heparin and oral anti-coagulants on Rabbits.
7. To identify the unknown anti-coagulant drug using Rabbits.
8. To demonstrate the graded Dose-Response curve of Acetylcholine on Rabbit intestine.
9. To identify unknown concentration of Acetycholine from graded Dose- Response curves.
Recommended Books (Pharmacology)
1. Goodman Gillman, Pharmacological basis of therapeutics.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology,
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics,
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi,
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung, B G, Basic and Clinical Pharmacology,
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001.
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993.
10. Qayum A Fundamentals of Experimental Pharmacology.
11. Bertram G K, Basic and Clinical Pharmacology, Paramount Publishing Business & Professional Group, USA, 6th Ed., 1995.
12. William F Ganong, W F, Review of Medical physiology, Prentice Hall International Inc, New Jersey.
Third Professional, Second Semester, Computer
COMPUTER AND ITS APPLICATIONS IN PHARMACY
(Theory)
Cr. Hr. 03
1. Fundamentals basic concept of computers History of Data Processing, Types of Computers, Components of a Computer, Computer System and Business Computer System, Backing Storage Devices, Unit of Memory, Viruses and Anti-viruses Issues.
2. System Analysis and Design what is a System? Steps in system life cycle, Data Gathering and Data Analysis, Designing a New System, Development and Implementation of New System, Documentation.
3. Data Processing Data Processing, The Data Processing Cycle, The Collection and Computing of data, Manual collection of data, The main methods of data input, Devices used to collect data, Data Verification, Data Validation, Output and Recording of data, Types of data processing systems, Types of Computer Operation, Batch Processing and Real-time Processing.
4. Data Communication Applications of Data Communication, Components of a data communication system, Rate of data Transmission, Computer Networks, Network Topology, Gateway, E-mail/Internet concepts.
COMPUTER AND ITS APPLICATIONS IN PHARMACY
(Laboratory)
Cr. Hr. 01
1. Internet and E-mail: Internet and Microsoft Internet Explorer 5, Addresses, Links and Downloading, Searching the Internet, E-mail and Newsgroups, Favorites, security and Customizing Explorer.
2. Web Page Development: Introduction to Front-page, Creating a First Web site, Basic
Formatting Techniques, Manipulating Tables within Front-page, Front-page, Picture and Multimedia, Hyper linking, Bookmarks and Image Maps, Introducing Front-page “components”, Front-page and Frames, Managing your Web, Good site design, Publishing and publicizing.
3. Complete Statistical Package like SPSS.
4. Languages
At least two prevailing languages will be taught.
Recommended Books
1. Elias M System Analysis. Award Galgotia Publications, New Delhi, 1989.
2. Peter Norton, Inside IBM PC. Brady Computer Books, New York, 1988.
3. Dennis N, MS-DOS. Jump Practice Hall Press, New York, 1987.
4. Peter Norton, PC-DOS. Brady Computer Books, New York, 1985.
(Theory)
Cr. Hr. 03
1. Fundamentals basic concept of computers History of Data Processing, Types of Computers, Components of a Computer, Computer System and Business Computer System, Backing Storage Devices, Unit of Memory, Viruses and Anti-viruses Issues.
2. System Analysis and Design what is a System? Steps in system life cycle, Data Gathering and Data Analysis, Designing a New System, Development and Implementation of New System, Documentation.
3. Data Processing Data Processing, The Data Processing Cycle, The Collection and Computing of data, Manual collection of data, The main methods of data input, Devices used to collect data, Data Verification, Data Validation, Output and Recording of data, Types of data processing systems, Types of Computer Operation, Batch Processing and Real-time Processing.
4. Data Communication Applications of Data Communication, Components of a data communication system, Rate of data Transmission, Computer Networks, Network Topology, Gateway, E-mail/Internet concepts.
COMPUTER AND ITS APPLICATIONS IN PHARMACY
(Laboratory)
Cr. Hr. 01
1. Internet and E-mail: Internet and Microsoft Internet Explorer 5, Addresses, Links and Downloading, Searching the Internet, E-mail and Newsgroups, Favorites, security and Customizing Explorer.
2. Web Page Development: Introduction to Front-page, Creating a First Web site, Basic
Formatting Techniques, Manipulating Tables within Front-page, Front-page, Picture and Multimedia, Hyper linking, Bookmarks and Image Maps, Introducing Front-page “components”, Front-page and Frames, Managing your Web, Good site design, Publishing and publicizing.
3. Complete Statistical Package like SPSS.
4. Languages
At least two prevailing languages will be taught.
Recommended Books
1. Elias M System Analysis. Award Galgotia Publications, New Delhi, 1989.
2. Peter Norton, Inside IBM PC. Brady Computer Books, New York, 1988.
3. Dennis N, MS-DOS. Jump Practice Hall Press, New York, 1987.
4. Peter Norton, PC-DOS. Brady Computer Books, New York, 1985.
Third Professional, First Semester, Pharmaceutics
PHARMACEUTICS-V (Dispensing Pharmacy)
(Theory)
Cr. Hr. 02
1. Basic Principles of Compounding and Dispensing Including: Weights and Measures, Calculations for compounding and Dispensing, Fundamental operations in Compounding, Containers and closures for Dispensed Products, Prescription-Handling (Parts of Prescription, Filling, Interpretation, Pricing) and Labelling of Dispensed Medication.
2. Extemporaneous Dispensing of: Solutions, Suspensions, Emulsions, Creams, Ointments, Pastes and gels, Suppositories and pessaries, Powders and granules and Oral unit dosage form.
3. Pharmaceutical Incompatibilities: Types of Incompatibilities, Manifestations, Correction and Prevention with reference to typical examples.
4. Classical dosage Forms.
5. I.V. Admixtures.
6. Radio-Pharmacy-Techniques and Applications.
PHARMACEUTICS-V (Dispensing Pharmacy)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Practical introduction to prescription-handling, interpretation, filling and Labeling.
1. Mixtures: Dispensing of simple mixtures containing soluble substances only, mixtures containing diffusable substances, indiffusable substances and mixtures forming precipitate.
2. Powders: Dispensing of simple powders, compound powders and effervescent powders for external use.
3. Incompatibility: Practical Importance of Incompatibilities.
4. Ointments And Creams: Dispensing of iodine and Methyl Salicylate ointment. Dispensing of cold cream and vanishing creams.
5. Cosmetics: Lipstic, talcum powder, after shave lotion, shaving cream. (Note: A minimum of 20 practicals will be conducted)
Recommended Books
1. Cooper and Guns, Dispensing, CBS Publishers & Distributors, New Delhi, 1986.
2. Hussa’s Dispensing.
3. Remington’s Pharmaceutical Sciences, Mack Publishing Company, USA, 2001.
4. Martindale's Extra Pharmacopoeia.
(Theory)
Cr. Hr. 02
1. Basic Principles of Compounding and Dispensing Including: Weights and Measures, Calculations for compounding and Dispensing, Fundamental operations in Compounding, Containers and closures for Dispensed Products, Prescription-Handling (Parts of Prescription, Filling, Interpretation, Pricing) and Labelling of Dispensed Medication.
2. Extemporaneous Dispensing of: Solutions, Suspensions, Emulsions, Creams, Ointments, Pastes and gels, Suppositories and pessaries, Powders and granules and Oral unit dosage form.
3. Pharmaceutical Incompatibilities: Types of Incompatibilities, Manifestations, Correction and Prevention with reference to typical examples.
4. Classical dosage Forms.
5. I.V. Admixtures.
6. Radio-Pharmacy-Techniques and Applications.
PHARMACEUTICS-V (Dispensing Pharmacy)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Practical introduction to prescription-handling, interpretation, filling and Labeling.
1. Mixtures: Dispensing of simple mixtures containing soluble substances only, mixtures containing diffusable substances, indiffusable substances and mixtures forming precipitate.
2. Powders: Dispensing of simple powders, compound powders and effervescent powders for external use.
3. Incompatibility: Practical Importance of Incompatibilities.
4. Ointments And Creams: Dispensing of iodine and Methyl Salicylate ointment. Dispensing of cold cream and vanishing creams.
5. Cosmetics: Lipstic, talcum powder, after shave lotion, shaving cream. (Note: A minimum of 20 practicals will be conducted)
Recommended Books
1. Cooper and Guns, Dispensing, CBS Publishers & Distributors, New Delhi, 1986.
2. Hussa’s Dispensing.
3. Remington’s Pharmaceutical Sciences, Mack Publishing Company, USA, 2001.
4. Martindale's Extra Pharmacopoeia.
Third Professional, First semester, Pharmaceutical Chemistry
PHARMACEUTICAL CHEMISTRY-III (Instrumentation-I)
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
Theory, Instrumentation and Pharmaceutical Applications of the following Spectroscopic Methods
1. Atomic Absorption and Emission Spectroscopy.
2. Molecular fluorescence spectroscopy.
3. Flame Photometry.
4. I.R. Spectroscopy.
5. Mass Spectroscopy.
6. NMR Spectroscopy.
7. UV/Visible Spectroscopy.
PHARMACEUTICAL CHEMISTRY-III (Instrumentation-I)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the requirements, e.g. Determination of the Purity and Composition of the unknown drugs by using at least each of the above techniques.
Recommended Books
1. Lough W J, High Performance Liquid Chromatography, Blacki Academic Press, New York, 1996.
2. William Kemp,Organic Spectroscopy, Ellsi Horwood, London, 1990.
3. M Aminuddin & Javed Iqbal, Theory and Practice of Chromatography, University Grants Commission, Islamabad-Pakistan (2000).
4. A H Beckett and J B Stennlake, Practical Pharmaceutical Chemistry, Part I and II, the Aulton Press, London.
5. A M Knevel and F E Digangi, Jenkins’s quantitative Pharmaceutical Chemistry, McGraw-Hill Book Company, New York.
6. Braithwaite and F J Smith, Chromatographic Methods, Chapman and Hall, London.
7. E Heftmann, Chromatography, Von Nostrond Reinheld Co, New York, 1975.
8. Pryde and M J Gilbert, Applications of High Performance Liquid Chromatography, Chapman & Hall, London, 1979.
9. E Stahl, Thin Layer Chromatography, Springer-Verlag, Berlin, 1969.
10. R Hamilton, Introduction to HPLC, P A Sewell, Chapman & Hall, London, 1982
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
Theory, Instrumentation and Pharmaceutical Applications of the following Spectroscopic Methods
1. Atomic Absorption and Emission Spectroscopy.
2. Molecular fluorescence spectroscopy.
3. Flame Photometry.
4. I.R. Spectroscopy.
5. Mass Spectroscopy.
6. NMR Spectroscopy.
7. UV/Visible Spectroscopy.
PHARMACEUTICAL CHEMISTRY-III (Instrumentation-I)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the requirements, e.g. Determination of the Purity and Composition of the unknown drugs by using at least each of the above techniques.
Recommended Books
1. Lough W J, High Performance Liquid Chromatography, Blacki Academic Press, New York, 1996.
2. William Kemp,Organic Spectroscopy, Ellsi Horwood, London, 1990.
3. M Aminuddin & Javed Iqbal, Theory and Practice of Chromatography, University Grants Commission, Islamabad-Pakistan (2000).
4. A H Beckett and J B Stennlake, Practical Pharmaceutical Chemistry, Part I and II, the Aulton Press, London.
5. A M Knevel and F E Digangi, Jenkins’s quantitative Pharmaceutical Chemistry, McGraw-Hill Book Company, New York.
6. Braithwaite and F J Smith, Chromatographic Methods, Chapman and Hall, London.
7. E Heftmann, Chromatography, Von Nostrond Reinheld Co, New York, 1975.
8. Pryde and M J Gilbert, Applications of High Performance Liquid Chromatography, Chapman & Hall, London, 1979.
9. E Stahl, Thin Layer Chromatography, Springer-Verlag, Berlin, 1969.
10. R Hamilton, Introduction to HPLC, P A Sewell, Chapman & Hall, London, 1982
Third Professional, First semester, Pharmacognosy
PHARMACOGNOSY-III
(Theory)
Cr. Hr. 03
1. SEPARATION AND ISOLATION OF PLANT CONSTITUTIONS: An introduction to chromatography and chromatographic techniques e.g. Adsorption Chromatography and Partition Chromatography.
2. CARBOHYDRATES: Introduction of carbohydrate.
(a) Sucrose and Sucrose containing drugs: Sucrose, Dextrose, Liquid glucose, Fructose, Lactose, Xylose, Caramel, Honey, Starch, Inulin, Dextrine etc.
(b) Cellulose and Cellulose Derivatives: Purified cotton, Powdered cellulose, Microcrystalline cellulose, Methyl cellulose, Sodium Carboxy-methyl cellulose.
(c) Gums and Mucilages: Tragacenth, Acacia, Sodium Alginate, Agar, Pectin.
3. GLYCOSIDES: Introduction, classification, chemistry and medicinal uses of:
(a) Cardioactive glycosides: Digitalis, Strophanthus and white squill.
(b) Anthroquinone glycosides: Cascara, Aloe, Rhubarb, Cochineal and Senna.
(c) Saponin glycosides: Glycyrrhiza, Sarsaparilla.
(d) Cyanophore glycosides: Wild cherry.
(e) Isothiocyanate glycosides: Black Mustard.
(f) Lactone glycosides: Cantharide.
(g) Aldehyde glycosides: Vanilla.
(h) Miscellaneous glycosides: Gentian,. Quassia, Dioscorea.
4. TANNINS: Introduction, classification, properties and chemical identity tests of Tannins and Tannin containing compounds. Detailed study of Hammamelis, Catechu and Nut Galls.
5. LIPIDS: Introduction. Detailed study of:
(a) Fixed Oils: Castor oil, cotton seed oil, olive oil, peanut oil, sun flower oil, corn oil, coconut oil, Almond oil, Linseed oil, Mustard oil, Sesame oil and soybean oil.
(b) Fats and Related Compounds: Theobroma oil and Lenolin.
(c) Waxes: Bees wax, carnauba wax, spermaceti and Jojoba oil.
PHARMACOGNOSY-III
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Extraction of the active constituents of crude drugs and chemical tests for their identification.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed.,
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto,
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission .
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors,
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission,
8. Youngkin H W, Text Book of Pharmacognosy. The Blakiston Co. Toronto, 6th Ed.,
(Theory)
Cr. Hr. 03
1. SEPARATION AND ISOLATION OF PLANT CONSTITUTIONS: An introduction to chromatography and chromatographic techniques e.g. Adsorption Chromatography and Partition Chromatography.
2. CARBOHYDRATES: Introduction of carbohydrate.
(a) Sucrose and Sucrose containing drugs: Sucrose, Dextrose, Liquid glucose, Fructose, Lactose, Xylose, Caramel, Honey, Starch, Inulin, Dextrine etc.
(b) Cellulose and Cellulose Derivatives: Purified cotton, Powdered cellulose, Microcrystalline cellulose, Methyl cellulose, Sodium Carboxy-methyl cellulose.
(c) Gums and Mucilages: Tragacenth, Acacia, Sodium Alginate, Agar, Pectin.
3. GLYCOSIDES: Introduction, classification, chemistry and medicinal uses of:
(a) Cardioactive glycosides: Digitalis, Strophanthus and white squill.
(b) Anthroquinone glycosides: Cascara, Aloe, Rhubarb, Cochineal and Senna.
(c) Saponin glycosides: Glycyrrhiza, Sarsaparilla.
(d) Cyanophore glycosides: Wild cherry.
(e) Isothiocyanate glycosides: Black Mustard.
(f) Lactone glycosides: Cantharide.
(g) Aldehyde glycosides: Vanilla.
(h) Miscellaneous glycosides: Gentian,. Quassia, Dioscorea.
4. TANNINS: Introduction, classification, properties and chemical identity tests of Tannins and Tannin containing compounds. Detailed study of Hammamelis, Catechu and Nut Galls.
5. LIPIDS: Introduction. Detailed study of:
(a) Fixed Oils: Castor oil, cotton seed oil, olive oil, peanut oil, sun flower oil, corn oil, coconut oil, Almond oil, Linseed oil, Mustard oil, Sesame oil and soybean oil.
(b) Fats and Related Compounds: Theobroma oil and Lenolin.
(c) Waxes: Bees wax, carnauba wax, spermaceti and Jojoba oil.
PHARMACOGNOSY-III
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Extraction of the active constituents of crude drugs and chemical tests for their identification.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed.,
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto,
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission .
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors,
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission,
8. Youngkin H W, Text Book of Pharmacognosy. The Blakiston Co. Toronto, 6th Ed.,
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