Mechanism of Action:
These are reversible inhibitors of cyclooxygenase.
Action:
These inhibit the synthesis of prostaglandins but not that of leukotrienes.
Pharmacokinetics:
It is absorbed orally. It has the ability to bind to plasma albumin. It undergoes hepatic metabolism and excreted by the kidney.
Therapeutic Uses:
It is used as anti-inflammatory mostly in the chronic treatment of rheumatoid arthritis and osteoarthritis. It is also anti-pyretic and anti-inflammatory.
Adverse effects:
• Headache, tinnitus and dizziness.
• GI disturbance ranging from dyspepsia to bleeding.
Subscribe to:
Post Comments (Atom)
-
Q: What do you know about ergot alkaloids? Ans: These include alkaloids which we get from the ergot fungus Claviceps purpurea or derived ...
-
(For detailed study of Pharmaceutical Incompatibility Click here) Multiple Choice Questions (MCQs) from Pharmaceutical Incompatibility in ...
-
Multiple Choice Questions (MCQs) of Powders and Granules from Pharmaceutics 1. _______ powders consist of more than one ingredients. a. Si...
No comments:
Post a Comment