Second Professional, First semester, Pharmaceutics

PHARMACEUTICS-III (Pharmaceutical Preparations-I)

(Theory)

Cr. Hr. 03

1. Introduction: Dosage form. Ingredients

2. Pharmaceutical Calculations: Some Fundamentals of Measurements and Calculations. The Metric System. The Common Systems. Conversions. Calculation of Doses. Reducing and Enlarging Formulas. Density, Specific Gravity & Specific Volume. Weights and Volumes of Liquids. Percentage Preparations. Isotonic Solutions. HLB Values. Industrial Calculations. Some calculations involving Hydrogen-ion concentration.

3. Galenical Preparations: Infusions. Decoctions. Extracts. Fluid extracts Tinctures. Aromatic Waters.

4. Extraction Processes: Maceration: Purpose and process. Percolation: Purpose and Process. Liquid-Liquid extraction. Large scale extraction.

5. Solvents used in Pharmaceutical Preparations.

6. Oral Solutions, Syrups, Elixirs and Spirits: Solutions and their preparation, dry mixtures for solution, oral rehydrate solutions, oral colonic leverage solution. Syrup: components and preparation of Syrups. Elixirs: Preparation of elixirs, medicated and non-medicated elixirs.

7. Oral Suspensions, Emulsions, Magma and Gels: Preparations, Examples, and Importance.

PHARMACEUTICS-III (Pharmaceutical Preparations-I)
(Laboratory)

Cr. Hr. 01

NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Prepartion of simple syrup, Orange syrup, Ferrous sulphate syrup, Cod Liver oil Emulsion, Liquid paraffin Emulsion, Throat paint (Mandle’s paint), Boroglycerine glycerite, Tannic acid glycerine, Spirit ammonia aromatic, Spirit of Ethyl nitrite. (A minimum of 10n practicals will be conducted)

Recommended Books

1. Michel E Aulton, Pharmaceutics, ELBS/Churchill Livingstone, London, 1998.

2. Bentley’s Book of Pharmaceutics, CBS Publishers & Distributors, New Delhi, 1986.

3. Pharmaceutics, the Science of Dosage Form Design. 2nd Ed., Haw Court Publisher, 2002.

4. E A Rawlins, Berdley’s Textbook of Pharmaceutics, edited by 8th (or recent edition) 1977. Macmillan Publishing Co Inc, New York.

5. Sprowl’s (Dittert L W, Eds.), American Pharmacy, 7th Ed, J B Lippincott Co, 1990.