Non-steroidal anti-inflammatory drugs

Acetic acid derivatives derivatives
Etodolac


Naphthyl acetic acid prodrug
Nabumetone

Cox-1 selective inhibitors
Acetylsalicylic acid ((Aspirin)at low dosage)

SalicylatesAcetylsalicylic acid (at high doses)
Amoxiprin
Benorylate/Benorilate
Choline magnesium salicylate
Ethenzamide
Faislamine
Methyl salicylate
Magnesium salicylate
Na. Salicylate
Na. thiosalicylate
Salicylic acid
Salicyl salicylate
Salicylamide

Difluorophenyl derivatives
Diflunisal

Indole acetic acids (Arylalkanoic acids)Aceclofenac
Acemethacin
Alclofenac
Bromfenac
Indomethacin
Oxametacin
Proglumetacin
Sulindac

Phenylacetic acid
Diclofenac potassium
Diclofenac sodium

Pyrolealkanoic acid
Tolmetin

2-Arylpropionic acids (profens)
Ibuprofen
Alminoprofen
Carprofen
Dexibuprofen
Dexketoprofen
Fenbufen
Fenoprofen
Flunoxaprofen
Flurbiprofen
Ibuproxam
Indoprofen
Ketoprofen (Actron, at least, has been withdrawn from the market.)
Ketorolac
Loxoprofen
Naproxen
Oxaprozin
Pirprofen
Suprofen
Tiaprofenic acid

N-Arylanthranilic acids (fenamic acids)Mefenamic acid
Flufenamic acid
Meclofenamate
Tolfenamic acid

Pyrazolidine derivatives
Phenylbutazone
Ampyrone
Apazone
Azapropazone
Clofezone
Kebuzone
Metamizole
Mofebutazone
Oxyphenbutazone
Phenazone
Sulfinpyrazone

OxicamsPiroxicam
Droxicam
Lornoxicam
Meloxicam
Tenoxicam

COX-2 inhibitorsCelecoxib (FDA has p-recautioned about its use)


OthersLicofelone
Omega-3 fatty acids

Licofelone acts by inhibiting LOX (lipooxygenase) & COX (cyclooxygenase)and hence known as
5-LOX/COX inhibitor.

Disease modifying anti-rheumatic agents (Slow acting anti-rheumatic agents):
Auranofin (Gold salts)
Aurothiomalate (Gold salts)
Chloroquine
Hydroxychloroquine
Leflunomide
Methotrexate
Penicillamine
Sulfasalazine

Anti-cytokines as anti-rheumatic agents:
Abatacept
Adalimumab
Anakinra
Etanercept
Infliximab
Rituximab

Further reading:
Safety and Efficacy of Non-Prescription (OTC) Analgesics and NSAIDs by K. D. Rainsford and M. C. Powanda

New NSAID appears effective for osteoarthritis: LOX-COX inhibitor.(Clinical Rounds)(licofelone): An article from: Family Practice News
by Mitchel L. Zoler

The Goodman and Gilman Manual of Pharmacology and Therapeutics by Laurence Brunton, Donald blumenthal, Iain buxton and Keith Parker

AHFS Drug Information 2008 (Ahfs Drug Information) by American Society of Health-system

Lippincott's Illustrated Reviews: Pharmacology, 4th Edition (Lippincott's Illustrated Reviews Series) by Richard A. Harvey, Pamela C. Champe, Richard Finkel, Luigi Cubeddu and Michelle A. Clarke
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