Cefpirome

It is a 4th generation cephalosporin.

Action:
It binds to penicillin binding protein and inhibits peptidoglycan synthesis in bacterial cell wall.

Uses:
It is active against gram positive and gram negative bacteria and is used for the treatment of lower respiratory tract infections and upper and lower urinary tract infections.

Cefozopran

It is a 4th generation cephalosporin. It is used parenterally.

Uses:
It is used against respiratory tract infections and urinary tract infections.

Cefepime

It is a 4th generation cephalosporin.

Action:
It has same action as that of other beta lactam antibiotics such as penicillin.

Uses:
It has an extended spectrum of activity against gram-positive and gram-negative bacteria and is used for the treatment of pneumonia and urinary tract infections.

Ceftobiprole

It is a fifth generation cephalosporin.

Action:
It inhibits penicillin binding proteins.

Uses:
It is used against infections caused by staphylococcus, streptococcus and enterococci.

Telithromycin

It is a ketolide antibiotic. It is derived from erythromycin.

Action:
It binds to 23S rRNA of the 50S ribosomal subunit of the bacteria having 25 times more affinity for macrolide resistant strains.

Uses:
It is used for the treatment of acute sinusitis, acute bronchitis and acute bacterial tonsilitis.

Cethromycin

It is a ketolide antibiotic.

Uses:It is an orphan drug for the treatment of post exposure inhalational anthrax. Research is on the way for its use in community acquired pneumonia (CAP).

Ansamycin

It is a ketolide antibiotic.

Action:
It inhibits DNA dependent RNA polymerase activity.

Uses:
It is used against many gram positive bacteria and some gram negative bacteria.