Monday, March 21, 2011

Carbidopa

Action:
It causes inhibition of the peripheral metabolism of levodpa results in helping levodopa to reach the brain easily.

Uses:
It is used in combination with levodopa for the patients of Parkinson's disease.

Sunday, March 20, 2011

Bromocriptine

It is available in the salt form of Bromocriptine Mesylate.

Action:
It is a dopamine agonist.
Uses:
It is used in the treatment of Parkinson's disease. It is also used in the treatment of Pituatory tumors, type 2 diabetes and neuroleptic malignant syndrome.

Biperiden

It is available in the salt form of Biperiden Hydrochloride or Biperiden lactate.

Action:
It possesses Anti-cholinergic properties.

Uses:
It is used in the management of Parkinson's disease.

Benztropine

It is available in the form of Benztropine Mesylate.

Action:
It possesses both Anti-cholinergic as well as Anti-histaminic properties. Its anti-cholinergic property is mainly important in the control of Parkinson's disease.
Uses:
It is used in the treatment of Parkinson's Disease.

Apomorphine

It is a derivative of morphine but is less active and work as a dopaminergic agonist.

Mechanism of Action:
It causes an increase in the dopamine amount in brain.
Uses:
It is used as an emetic and in little doses can also be used as sedative. It is also used as an Anti-parkinsonian agent.

Amantadine

It is used in the form of Amantadine Hydrochloride.

Mechanism of Action:
It helps in the treatment of Parkinson's disease by increasing the amount of dopamine in brain.

Uses:
It is an Anti-viral drug, used in the symptomatic or prophylactic treatment of Influenze-A, and is also used in the treatment of Parkinson's Disease.
It may also help in reducing dyskinesias.

Adverse Effects:
It may cause seizures in elderly people when used in high doses.

Saturday, March 19, 2011

Atenolol

Therapeutic uses:

1. Hypertension
2. Angina pectoris
3. Cardiac dysarrhythmias

Safe in patients with diabetes or peripheral vascular disease