Saturday, April 9, 2011

Classification of Anti-hypertensive drugs

1. Adrenergic neuron blocking drugs:

Bethanidine, Methoserpidine, Reserpine, Syrosingopine, Guanthedine

2. Antihypertensive direct vasodilators:
Diazoxide, Dihydralazine, Hydralazine, Minoxidil, Sodium nitroprusside

3. Centrally acting sympatholytic antihypertensive drugs:
Clonidine, Guanabenz, Guanfacine, Labetol, α-methyldopa

4. Ca2+ channel blockers:
a. Diphenylalkylamines:
Verapamil

b. Benzothiazepines:
Diltiazem

c. Dihydropyridines:
Amlodipine, Felodipine, Isradipine, Nicardipine, Nifedipine, Nisoldipine, Nitrendipine

5. Diuretics:
Bumetanide, Furosemide, Hydrochlorthiazide, Methyclothiazide, Polythiazide, Quinthazone, Spironolactone, Triamterene, Trichlomethiazide

6. Drugs acting on Renin angiotensin system:
a. ACE inhibitors:
Benazepril, Captopril, Enalapril, Fosinopril, Lisinopril, Moexipril, Perindopril, Quinapril, Ramipril, Trandolapril

b. Angiotensin II receptor antagonist:
Candesartan cilexetil, Losartan, Saralasin, Valsartan

7. Drugs acting on Serotonin receptors:
Ketanserin, Urapidil

8. Ganglionic blocking agents:
Mecamylamine hydrochloride, Pentamethonium bromide, Pentolinium, Trimethaphan camsylate

9. Monoamine oxidase inhibitor:
Pargyline hydrochloride

10. Peripheral anti-adrenergic drugs:
a. α-blockers:
Phenoxybenzamine, Phentolamine,

b. α1-blockers:
Doxazosin, Prazosin, Terazosin

c. β-blockers:
Atenolol, Metoprolol, Nadolol, Propranolol, Timolol

d. α and β blockers:
Labetalol

11. Plant products:
Cryptenamine acetates, Reserpine, Veratridine

12. Miscellaneous:
Bretylium

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