It also has a potent non-selective β-blocking agent.
As indicative of β-blocking agents, it also has the ability of decreasing mortality from acute myocardial infarction.
Actions:
It causes the inhibition of potassium outflow (also referred to as delayed rectifier). This inhibition increases both
1. Repolarization and
2. Action potential duration
And have the ability of prolonging the effective refractory period.
It has the ability of suppressing the ectopic beats and decreases myocardial oxygen demand. In the case of myocardial ischemia, it has prominent anti-fibrillatory affect.
Therapeutic uses:
1. Myocardial Ischemia
2. Sustained ventricular tachycardia
Adverse effects:
Prolonging the QT interval leading to torsade de pointes syndrome.
Sunday, March 6, 2011
Subscribe to:
Post Comments (Atom)
-
Q: What do you know about ergot alkaloids? Ans: These include alkaloids which we get from the ergot fungus Claviceps purpurea or derived ...
-
(For detailed study of Pharmaceutical Incompatibility Click here) Multiple Choice Questions (MCQs) from Pharmaceutical Incompatibility in ...
-
Multiple Choice Questions (MCQs) of Powders and Granules from Pharmaceutics 1. _______ powders consist of more than one ingredients. a. Si...
No comments:
Post a Comment