Second Professional, Second Semester, Pharmaceutics

Pharmaceutics-IV (Pharmaceutical Preparations-II)
(Theory)

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1. TRANSDERMAL DRUG DELIVERY SYSTEMS: Introduction of Ointments, Creams, Pastes, Poultice, Plasters, Lotions, Liniments, Topical gels, Topical Tinctures, Collodions, Topical solutions, Topical Powders, Percutaneous absorption, Transdermal systems in use.

2. OPHTHALMIC, NASAL AND OTIC PREPARATIONS: Ophthalmic solutions, suspensions, ointment, inserts, contact lens solutions. Nasal decongestant solutions, Decongestant inhalers. Ear preparations: Antiinfective, anti-inflammatory and analgesic.

3. SUPPOSITORIES AND VAGINAL SUPPOSITORIES: Semi-solid Preparations, Suppositories bases, preparation, packaging and storage, Solutions/Anemas.

4. AEROSOLS, INHALATIONS AND SPRAYS: Aerosol: Principle, container and valve assembly, Propellants, filling, testing, packaging, labeling and storage.

5. POWDERS, CAPSULES, and TABLET DOSAGE FORMS: Preparation of Powders, mixing of powders, uses and packaging of powders, granules, effervescent, granulated salts. Hard gelatin capsules, capsule sizes, preparation of filled hard gelatin capsules, soft gelatin capsules, preparation and its application. Tablets, their types, characteristics and methods of preparation.

6. INTRODUCTION TO PARENTERALS: Official types of injections, solvents and vehicles for injections, added substances.

7. A brief introduction to oral hygiene products.

Pharmaceutics-IV (Pharmaceutical Preparations-II)
(Laboratory)

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NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Prepartion of Methyl salicylate ointment, Sulpher ointment, Calamine lotion, Iodine tincture, Preparations of oral

hygiene products, Poultice of Kaolin, Effervescent granules, Distilled Water for injections.

(A minimum of 10n practicals will be conducted)

Recommended Books

1. Michel E Aulton, Pharmaceutics, ELBS/Churchill Livingstone, London, 1998.
2. Bentley’s Book of Pharmaceutics, CBS Publishers & Distributors, New Delhi, 1986
3. Pharmaceutics, The Science of Dosage Form Design. 2nd Ed., HawCourt Publisher, 2002.
4. E A Rawlins, Berdley’s Textbook of Pharmaceutics, edited by 8th time (or recent edition) 1977. Macmillan Publishing Co Inc, New York.
5. Sprowl’s (Dittert L W; Ed.), American Pharmacy, 7th Ed., J B Lippincott Co, 1990.