Monday, April 11, 2011

Chloroquine and hydroxychloroquine

These drugs are mainly used in malaria.

Mechanism of action:
These drugs may cause the lowering of T lymphocytes for action in Rheumatoid arthritis.

These drugs are used in Rheumatoid arthritis, when NSAIDs are not effective to that extent. They may be used alone or in combination with other NSAIDs. When it is used in combination it must be used in lower doses.

These drugs slow the gradual change in the bones due to continuous wear & tear and sometimes they may cause temporary disappearance of the disease.

Adverse effects:
This may cause ocular toxicity, nausea, vomiting and dyspepsia.
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