Tuesday, March 29, 2011

PEGylated dosage forms

PEGylated dosage form refers to the attachment of the polythylene glycol polymer chains to a drug concealing the agent from the immune sytem of the body reducing immunogenicity resulting in prolonged circulatory time.

Examples:
PEGylated interferon alpha is in use for the treatment of hepatitis B and C.
PEGylated liposome having doxorubicin is used in the treatment of cancer.
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