It belongs to the class of diuretic sulfonamide. It is a metanilamide derivative.
It interferes with renal cAMP and/or results in the inhibition of the sodium/potassium ATPase pump. It causes dilation of blood vessels in the kidneys and thus increases renal blood flow.
Its half life is 1-1.5 hour. Its onset of action is 30 minutes to 90 minutes and duration of action is 4-6 hours.
It is used as diuretic and can also be used in the treatment of edema associated with congestive heart failure. It is also used for Hepatic Cirrhosis.
Nausea, vomiting, rashes and abdominal pain
Furosemide and bumetanide weakly inhibit carbonic anhydrase.