Authentic and to the Point Source in the Ocean of Web
Monday, March 2, 2009
Its full name is 1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine .(Thurmond et al.) It is developed by Johnson and Johnson Pharmaceutical R & D as an anti-inflammatory agent. It is better in the treatment of itching. (wikipedia.com, 2009)
It blocks the chemotaxis induced by histamine in mouse. (Thurmond et al.)
References: 1. JNJ 7777120 (2009). wikipedia, retrieved on 03. 03. 2009 from http://en.wikipedia.org/wiki/JNJ_7777120
2. Thurmond, R. L., Desai, P. J., Dunford, P. J., Leung, W. P. F., Hofstra,C. L., Jiang, W., Nguyen, S., Riley, J. P., Sun, S., Williams, K. N., Edwards, J. P., and Karlsson, L., (2004).Journal of Pharmacology And Experimental Therapeutics, 404-413.