Sunday, November 30, 2008

Maceration

Introduction:
Maceration is the process of softening and separating a substance by proper soaking it in particular liquid.

Procedure:
In this process, the drug previously powdered and weighed, is put alongwith the menstruum, which is that particular liquid such as ethyl acetate, ethanol or methanol, in a stoppered container.

This thing is then placed at a safe place for a definite period of time such as from two to seven days. Shaking must be done along the time.

Then the product is taken and filtered. Here, the residue obtained on the filter is known as the marc and it is pressed thoroughly, so that there will be no loss. The residue be clarified by subsidence or filtration.

References:

Encyclopedia Britannica 2009 Deluxe (Avanquest)

British Pharmacopoeia 2009 (British Pharmacopoeia) by British Pharmacopoeia Commission

Remington: The Science and Practice of Pharmacy

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