Tuesday, March 22, 2011

Sulfametopyrazine

(It is now withdrawn)
It is a long acting sulfonamide.

Action:
It competitively inhibits the bacterial enzyme dihydropteroate synthetase.

Uses:
It is used for Urinary tract infections, Respiratory tract infections and malaria.

Sulfamethoxy-pyridazine

It is a long acting sulfonamide.

Uses:
It is used to treat Urinary Tract Infections, Pneumonia and bronchitis.

Sulfadoxine

Sulfadoxine is an intermediate to long acting sulfonamide.

Uses:
It is generally used in combination with other drugs

Sulfacetamide

It is an intermediate acting sulfonamide and is available in the salt form alongwith sodium.

Mechanism of Action:
It competitively inhibits the bacterial enzyme para-aminobenzoic acid resulting in the inhibition of the synthesis of the folic acid.

Uses:
It is used in the treatment of skin infections and orally it is useful in the treatment of Urinary tract infections.

Monday, March 21, 2011

Sulfisomidine

It is also known as sulfasomidine and it is a short acting sulfonamide.

It is similar to sulfadimidine.

Sulfisoxazole

It is a short acting sulfonamide.

Mechanism of Action:
It inhibits the folic acid production of bacteria by competitive inhibition of the enzyme dihydropteroate synthetase.

Uses:
It is used for the treatment of Urinary Tract Infections, Acute otitis media, meningococcal meningitis, malaria and other bacterial infections.

Sulfamethoxazole

It is a short acting bacteriostatic sulfonamide.

Action:
It hinders folic acid synthesis in susceptible bacteria.

Uses:
It is used to treat prostatitis, bronchitis and Urinary tract infections.

Brand Names:
•Apo-Sulfamethoxazole

•Azo Gantanol
•Azo-Gantanol
•Bactrimel
•Gamazole
•Gantanol
•Gantanol-DS
•Metoxal
•Radonil
•Septran
•SIM
•Simsinomin
•Sinomin
•Sulfamethalazole
•Sulfamethoxazol
•Sulfamethoxizole
•Sulfamethylisoxazole
•Sulfisomezole
•Sulpha-Methoxizole
•Sulphamethalazole
•Sulphamethoxazol
•Sulphamethoxazole
•Sulphamethoxazole BP 98
•Sulphamethylisoxazole
•Sulphisomezole
•Trib
•Urobak