Tuesday, March 22, 2011

Sulfaphenazole

(It is in experimental stages.)

It is a long acting sulfonamide antibacterial.

Action:
It specifically inhibits CYP2C9 i.e an important cytochrome P450 enzyme important in the oxidation of endogenous compounds.

Sulfametopyrazine

(It is now withdrawn)
It is a long acting sulfonamide.

Action:
It competitively inhibits the bacterial enzyme dihydropteroate synthetase.

Uses:
It is used for Urinary tract infections, Respiratory tract infections and malaria.

Sulfamethoxy-pyridazine

It is a long acting sulfonamide.

Uses:
It is used to treat Urinary Tract Infections, Pneumonia and bronchitis.

Sulfadoxine

Sulfadoxine is an intermediate to long acting sulfonamide.

Uses:
It is generally used in combination with other drugs