It is an aminoglycoside antibiotic derived from "Streptomyces" bacteria.
Action:
It inhibits polypeptide synthesis.
Tuesday, March 22, 2011
Kanamycin
It is an aminoglycoside derived from "Streptomyces" bacteria.
Action:
It binds irreversibly to 30S ribosomal subunit proteins and 16S rRNA. This results in the non-functional peptides.
Uses:It is used for the treatment of infections caused by E.coli and proteus species.
Action:
It binds irreversibly to 30S ribosomal subunit proteins and 16S rRNA. This results in the non-functional peptides.
Uses:It is used for the treatment of infections caused by E.coli and proteus species.
Neomycin
It is an aminoglycoside derived from "Streptomyces" bacteria.
Action:
It binds to 30S ribosomal subunit and resulting in the production of non-functional peptide.
Uses:
It is used topically for the treatment of superficial eye infections and may be used orally for the treatment of hepatic encephalopathy.
Action:
It binds to 30S ribosomal subunit and resulting in the production of non-functional peptide.
Uses:
It is used topically for the treatment of superficial eye infections and may be used orally for the treatment of hepatic encephalopathy.
Streptomycin
It is an aminoglycosides derived from "Streptomyces" bacteria.
Action:
It causes disruption in the initiation and elongation steps in protein synthesis by binding to the 30S ribosomal subunit of the the susceptible organism.
It is used for the treatment of tuberculsosis.
Adverse effects:It is ototoxic and nephrotoxic. It may also cause vertigo and hearing loss.
Action:
It causes disruption in the initiation and elongation steps in protein synthesis by binding to the 30S ribosomal subunit of the the susceptible organism.
Mainly active against extracellular tubercle bacilli as it penetrates poorly into cells.
Uses:It is used for the treatment of tuberculsosis.
Adverse effects:It is ototoxic and nephrotoxic. It may also cause vertigo and hearing loss.
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