Action:
It is more potent in action than naproxen and indomethacin. It is cyclooxygenase inhibitor.
Pharmacokinetics:
It accumulates in the synovial fluid. It is excreted into urine.
Therapeutic Uses:
It is used for the long term treatment of:
• Rheumatoid arthritis
• Osteoarthritis
• And ankylosing spondylitis.
Adverse effects:
Its adverse effects are similar to those of the NSAIDs.
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