Fifth Professional, Second Semester, Pharmaceutical Technology

PHARMACEUTICS-XIX (Pharmaceutical Technology-II)
(Theory)


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1. MODIFIED DRUG RELEASE DOSAGE FORM:

The concept of sustained release, First order release approximation, Multiple dosing, Implementation of designing, Approaches based upon dosage form modification, Product evaluation and testing, Matrices tablets, Control release technology, Microencapsulation, Method of particle coating and Instrumentation in granule manufacturing.

2. PHARMACEUTICAL BIOTECHNOLOGY:

Biotechnological aspects in the product development, Fundamentals of Genetic Engineering and its Application in Medicine, Principle, Synthesis and Application of Monoclonal, Antibodies, Introduction to Gene therapy, Immobilized Enzymes and their application in Medicine, General Principle and Methods of Microbial Assay.

PHARMACEUTICS-XIX (Pharmaceutical Technology-II)
(Laboratory)

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NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Microbial assay, Particle size analysis using various methods, Stability studies of Pharmaceuticals, Coating of particles and To prepare, examine and control specifications of packaging materials.

Recommended Books

1. Anya M Hellery, Drug delivery and targeting, Taylor & Francis, London, 2001.
2. Joseph R Robinson Controlled drug delivery, Marcel & Dakker Inc, New York, 2nd Ed., 1987.
3. T V Ramabhadran, Pharmaceutical design and development, Ellis Horwood, New York, 1994.
4. M E Aulton, Pharmaceutics: Science of Dosage Forms Design, ELBS/Churchill Livingstone, London, 1998.
5. Banker, Modern pharmaceutics, Marchell Dakker Inc, New York, 1990.
6. John A Bontempo, Development of biopharmaceutical parenteral dosage forms, Marchell Dakker Inc, New York, 1997.
7. N K Jain, Controlled and Novel drug delivery, CBS Publishers and Distributers, New Dehi, 1997.
8. Ansel, Pharmaceutical Dosage Form in Drug Delivery System, Lee and Febiger, London, 1990.
9. Attaurahman and M I Chaudry, Bioassay techniques for drug development, CRC Press, LLC, USA, 2001.
10. Pramod K Gupta, Inject able drug development, CRC Press, LLC, USA, 1999.
11. H John Smith, Introduction to the principals of drug design and action, CRC Press, LLC, USA, 1998.
12. Rong Liu, Water Insoluble Drug Formulations, CRC Press, LLC, USA, 2000.
13. Peter Blaisdell, Twenty First Century Pharmaceutical Development. CRC Press, LLC, USA, 2000.
14. Lachman L, Theory and Practice of Industrial Pharmacy, Lee & Febiger, Philadelphia, 3rd Ed., 1986.