Sunday, March 6, 2011

Class III Antiarrhythmic Drugs

These are potassium channel blockers.


Actions:
They reduce the outward flow of potassium during repolarization phase of cardiac cells.

They have the ability of increasing the duration of action potential without changing Phase 0 of depolarization or the resting membrane potential.

They also have the ability of prolonging the effective refractory period.

Class III antiarrhythmic agents have the potential of induction of arrhythmias.
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