Sunday, March 6, 2011

Class III Antiarrhythmic Drugs

These are potassium channel blockers.

They reduce the outward flow of potassium during repolarization phase of cardiac cells.

They have the ability of increasing the duration of action potential without changing Phase 0 of depolarization or the resting membrane potential.

They also have the ability of prolonging the effective refractory period.

Class III antiarrhythmic agents have the potential of induction of arrhythmias.
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