Wednesday, March 23, 2011

Sorangicin-A

It is a broad spectrum macrolide antibiotic. It is isolated from Sorangium cellulosum.

Quinopristin/dalfopristin

It is a macrolide antibiotic.

Action:
Dalfopristin binds to 23S portion of 50S ribosomal subunit and Quinopristin binds to a nearby site of 50S ribosomal subunit and in this way they causes the inhibition of protein synthesis.

Uses:It is used for the treatment of Staphylococcal infections and infections caused by Enterococcus faecium.

Pristinamycin

It is a macrolide antibiotic.

Uses:It is used in the treatment of staphylococcal infections and to some extent for streptococcal infections.

Lincomycin

It is a macrolide antibiotic.

Mechanism of Action:
It binds to 50S ribosomal subunit of bacteria and results in decreased protein synthesis.

Uses:It is used in the treatment of infections caused by staphylococcus and streptococcus.

Clindamycin

It is a macrolide antibiotic.

Mechanism of Action:
It binds to 50S ribosomal subunit of bacteria resulting in decreased protein synthesis.

Uses:It is used for osteomyelitis, dental infections and diabetic foot ulcers.

Maridomycin

It is a macrolide antibiotic.

Uses:It is an antibiotic and is also used for the Uterine myoma and endometriosis.

Kejanimicin

It is a macrolide antibiotic and is structurally related to tetrocarcin.
Kejanolide is the aglycon portion of the Kajanamicin.