Tuesday, July 8, 2008

Carbomer

Carbomer is a type of molecule which is usually obtained by the insertion of Carbon units in a certain molecule. It is a polymer of acrylic acid crosslinked with a polyfunctional molecule or compound such alkyl ethers of sucrose and/or pentaerythritol. [1]

It is also referred to as polyacrylic or polyacrylate.

Types of Carbomers:
In the National Formulary, there are six types of carbomers' monographs:
1. Carbomers 910
2. Carbomers 934
3. Carbomers 934P (The suffix "P" shows that this is a highly purified product and can be used orally). [2]
4. Carbomers 940
5. Carbomers 941
6. Carbomers 1342 [1]

Properties of Carbomers:[2]
1. White powder (Fluffy)
2. Hygroscopic
3. Soluble in water
4. pH of 1% aquous dispersion is 2.5 to 3.0
5. Incompatible with phenol and resorcinol
6. Products of Carbomers are sensitive to light

Uses:
It is mostly used as a suspending agent in Pharmaceutical industry. They are also used as gelling agents at the concentration of 0.5 to 2.0 % in water. [1]

References:
[1]Page # 2444, Encyclopedia of Pharmaceutical Technology by James Swarbrick.

[2] 18.18, Part 4 Pharmaceutical necessities, A Practical Guide to Contemporary Pharmacy Practice by Judith E. Thompson and Lawrence Davidow.

Further Reading:
A Practical Guide to Contemporary Pharmacy Practice by Judith E. Thompson and Lawrence Davidow

The National Formulary X : Tenth Edition

Martindale: The Complete Drug Reference, 35th Edition: Book and CD-ROM Package

Remington: The Science and Practice of Pharmacy

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Monday, July 7, 2008

Macromolecular

Related to molecules having a large molecular mass may be in the range from thousnads to millions.
Biochemically, proteins, lipids, carbohydrates, nucleic acids, polysaccharides are included.

Imbibe

Absorb (water, solution etc.)

FORECAST Function in Microsoft Excel