Their findings are consistent with observational reports suggesting the acceleration of recovery in patients who are receiving amantadine and the deceleration or loss of function after treatment is discontinued.
Researchers worked on 184 patients, who were in minimal conscious state for 4-16 weeks after severe brain injury. They divided the patients in two groups, one receiving the drug, amantadine, while the other received the dummy medicine i.e. placebo, for 4 weeks. Researchers have found that the group, which received the flu drug showed rapid improvement. They were better able to follow commands and reliably saying yes or no. They were also better able to use a spoon or hairbrush.