Wednesday, March 2, 2011

Second Professional, Second Semester, Microbiology


Cr. Hr. 03

Note:- The topics will be taught with special reference to their Pharmaceutical Applications.

2. INDUSTRIAL MICROBIOLOGY: Introduction to Sterilization/Disinfection. Fermentation. Pharmaceutical products produced by fermentation process (Penicillins, Cepalosporins, Gentamycin, Erythromycin, Tetracyclines, Rifamycin, Griseofulvin)

3. IMMUNOLOGY: Introduction, Types of Imunity: Specific and nonspecific (Cellular basis of Immune response. Immunity, autoimmunity, tolerance. Antigen. Antibodies). Antigen-Antibody reactions and their clinical and diagnostic applications. Hypersensitivity and allergy. Drug allergy mechanism. Vaccination: Introduction and aims. Types of Vaccines. Current vaccine practices.

4. FACTORY AND HOSPITAL HYGIENE AND GOOD MANUFACTURING PRACTICE: Introduction, Control of Microbial contamination during manufacture, Mnaufacture of Sterile products, A Guide to Current Good Pharmaceutical Manufacturing Practices.

Cr. Hr. 01

NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Sterilization of Glassware and pharmaceutical products by various methods. Microbiological assays of: Antibiotics and vitamins.

Recommended Books

1. Jawetiz, Medical Microbiology and Immunology, 5th Ed., Churchill Livingstone, London, 1998.
2. W B Hugo & A D Russell, Pharmaceutical Microbiology, Black Well Science Ltd, London, 6th Ed., 1998.
3. Lippincot, Microbiology by lipponcott, William & Willkin, USA, 2001.
4. Alcamo, Introduction to Microbiology, John Bartlett Publishers, 6th Ed., 2003.
5. Collin and Lynes, Microbiological Methods, Vutterworth Heineman, Oxford, 1995.
6. M Mekallee, Microbiology: Essentials and Application, McGraw-Hill Inc, 2nd Ed.
7. Singleton and Sainsbury, Dictionary of Microbiology and Molecular biology, John Willey & Sons, New York, 2000.
8. Pelczar, Microbiology, McGraw-Hill Inc, 1996.
9. Prescott, Harley, Microbiology, 2nd Ed., Klein Wm C Brown Publishers, 2001.
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