PHARMACEUTICS-IV (Community Pharmacy)
(Theory)
Cr. Hr. 04
1. DEFINITIONS AND BACKGROUND.
2. PUBLIC HEALTH AND COMMUNITY PHARMACY: Epidemeology & its Control, Preventive Health (EPI & CDC), Family Planning and Health Policy & National Drug Policy.
3. PATIENT ASSESSMENT.
4. MEDICAL COMPLICATION OF DRUG TAKING: General and Socioeconomic Aspects.
5. PATIENT PHARMACIST COMMUNICATION.
6. PATIENT EDUCATION AND COUNCELLING.
7. CONTROL OF DRUG ABUSE AND MISUSE.
8. ROLE OF PHARMACIST: As Public Health Educator in the Community for Drug Monitoring and Drug Information.
Recommended Books
1. Roy Robertson, Management of Drug Users in the Community: A Practical Handbook.
2. Remington’s Pharmaceutical Sciences, Mack Publishing Company, USA, 2001.
3. Martindale's Extra Pharmacopoeia.
Showing posts with label Pharmacy Syllabus in Pakistan. Show all posts
Showing posts with label Pharmacy Syllabus in Pakistan. Show all posts
Thursday, March 3, 2011
Third Professional, Second Semester, Pharmaceutical Chemistry
PHARMACEUTICAL CHEMISTRY-IV (Instrumentation)
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
1. CHROMATOGRAPHIC METHODS: Column Chromatography, Thin Layer Chromatography, Gas Liquid Chromatography, HPLC and GCMS.
2. ELECTRO CHEMICAL METHODS: Potentiometry, Polarography and Radiochemical Techniques.
3. DIFFERENTIAL SCANNING CALORIMETRY.
PHARMACEUTICAL CHEMISTRY-IV (Instrumentation)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the requirements, e.g. Determination of the Purity and Composition of the unknown drugs by using at least each of the above techniques.
Recommended Books
1. Lough W J, High Performance Liquid Chromatography, Blacki Academic Press, New York, 1996
2. William Kemp,Organic Spectroscopy, Ellsi Horwood, London, 1990. 3. M Aminuddin & Javed Iqbal, Theory and Practice of Chromatography, University Grants Commission, Islamabad-Pakistan (2000).
4. A H Beckett and J B Stennlake, Practical Pharmaceutical Chemistry, Part I and II, the aulton Press, London.
5. A M Knevel and F E Digangi, Jenkins’s quantitative Pharmaceutical Chemistry, McGraw-Hill Book Company, New York.
6. A Braithwaite and F J Smith, Chromatographic Methods, Chapman and Hall, London.
7. E Heftmann, Chromatography, Von Nostrond Reinheld Co, New York, 1975.
8. A Pryde and M J Gilbert, Applications of High Performance Liquid Chromatography, Chapman & Hall, London, 1979.
9. E Stahl, Thin Layer Chromatography, Springer-Verlag, Berlin, 1969.
10. R Hamilton, Introduction to HPLC, P A Sewell, Chapman & Hall, London, 1982.
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
1. CHROMATOGRAPHIC METHODS: Column Chromatography, Thin Layer Chromatography, Gas Liquid Chromatography, HPLC and GCMS.
2. ELECTRO CHEMICAL METHODS: Potentiometry, Polarography and Radiochemical Techniques.
3. DIFFERENTIAL SCANNING CALORIMETRY.
PHARMACEUTICAL CHEMISTRY-IV (Instrumentation)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the requirements, e.g. Determination of the Purity and Composition of the unknown drugs by using at least each of the above techniques.
Recommended Books
1. Lough W J, High Performance Liquid Chromatography, Blacki Academic Press, New York, 1996
2. William Kemp,Organic Spectroscopy, Ellsi Horwood, London, 1990. 3. M Aminuddin & Javed Iqbal, Theory and Practice of Chromatography, University Grants Commission, Islamabad-Pakistan (2000).
4. A H Beckett and J B Stennlake, Practical Pharmaceutical Chemistry, Part I and II, the aulton Press, London.
5. A M Knevel and F E Digangi, Jenkins’s quantitative Pharmaceutical Chemistry, McGraw-Hill Book Company, New York.
6. A Braithwaite and F J Smith, Chromatographic Methods, Chapman and Hall, London.
7. E Heftmann, Chromatography, Von Nostrond Reinheld Co, New York, 1975.
8. A Pryde and M J Gilbert, Applications of High Performance Liquid Chromatography, Chapman & Hall, London, 1979.
9. E Stahl, Thin Layer Chromatography, Springer-Verlag, Berlin, 1969.
10. R Hamilton, Introduction to HPLC, P A Sewell, Chapman & Hall, London, 1982.
Third Professional, Second Semester, Pharmacognosy
PHARMACOGNOSY-IV
(Theory)
Cr. Hr. 03
1. VOLATILE OILS (ESSENTIAL OILS): Introduction, significance, methods of obtaining volatile oils, chemistry and classification of:
(a) Hydrocarbon volatile oils: Cubeb and Terpentine oil.
(b) Alcoholic volatile oils: Peppermint, Coriander and Cardamom.
(c) Aldehydic volatile oils: Bitter orange peel, sweet orange peel, lemon, cinnamon and bitter almond oil.
(d) Ketonic volatile oils: Camphor, spearmint, caraway, Buchu.
(e) Phenolic volatile oils: Clove, Thyme.
(f) Phenolic ether volatile oils: Fennel, Anise, Myristica.
(g) Oxide volatile oils: Eucalyptus, chenopodium.
(h) Ester volatile oils: Rosemary.
(i) Miscellaneous volatile oils: Allium, Anethum.
2. RESINS AND RESIN COMBINATION: Introduction, properties and difference between glycoresins, oleoresins, oleo-gum resins and balsams.
(a) Resins: Rosin, Cannabis.
(b) Glycoresins: Podophyllum, Jalap, Ipomoea, Colocynth.
(c) Oleoresins: Terpentine, Capsicum, Ginger.
(d) Oleo-gum resins: Asafoetida, Myrrh.
(e) Balsams: Storax, Peruvian balsam, Tolu balsam, Benzoin.
3. ALKALOIDS: Introduction, Properties, Cassification, Function of alkaloids in plants, Methods of extraction and identification tests.
(a) Pyridine — Piperidine Alkaloids: Areca nut, Lobelia, Tobacco.
(b) Tropane Alkaloids: Belladonna, Hyoscyamus, Stramonium.
(c) Quinoline Alkaloids: Cinchona.
(d) Isoquinoline Alkaloids: Ipecacuanha, Opium.
(e) Indole alkaloids: Rauwolfia, catharanthus, nux vomica, physostigma, ergot.
(f) Imidazole alkaloids: Pilocarpus.
(g) Steroidal alkaloids: Veratrum.
(h) Alkaloidal amines: Ephedra, colchicum.
(i) Purine Bases: Tea, Coffee.
4. TUMOUR INHIBITORS FROM PLANT: Detailed study of various antitumour agents isolated from plants.
PHARMACOGNOSY-IV
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Isolation and separation of active constituents of crude drugs by paper and thin layer chromatography.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed., Lea and Febiger, Philadelphia, 1988.
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto, 2002.
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission Monograph Series, Islamabad, pp74, 1985.
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission, Islamabad, 1985.
8. Youngkin H W, Text Book of Pharmacognosy, The Blakiston Co, Toronto, 6th Ed., 1948.
(Theory)
Cr. Hr. 03
1. VOLATILE OILS (ESSENTIAL OILS): Introduction, significance, methods of obtaining volatile oils, chemistry and classification of:
(a) Hydrocarbon volatile oils: Cubeb and Terpentine oil.
(b) Alcoholic volatile oils: Peppermint, Coriander and Cardamom.
(c) Aldehydic volatile oils: Bitter orange peel, sweet orange peel, lemon, cinnamon and bitter almond oil.
(d) Ketonic volatile oils: Camphor, spearmint, caraway, Buchu.
(e) Phenolic volatile oils: Clove, Thyme.
(f) Phenolic ether volatile oils: Fennel, Anise, Myristica.
(g) Oxide volatile oils: Eucalyptus, chenopodium.
(h) Ester volatile oils: Rosemary.
(i) Miscellaneous volatile oils: Allium, Anethum.
2. RESINS AND RESIN COMBINATION: Introduction, properties and difference between glycoresins, oleoresins, oleo-gum resins and balsams.
(a) Resins: Rosin, Cannabis.
(b) Glycoresins: Podophyllum, Jalap, Ipomoea, Colocynth.
(c) Oleoresins: Terpentine, Capsicum, Ginger.
(d) Oleo-gum resins: Asafoetida, Myrrh.
(e) Balsams: Storax, Peruvian balsam, Tolu balsam, Benzoin.
3. ALKALOIDS: Introduction, Properties, Cassification, Function of alkaloids in plants, Methods of extraction and identification tests.
(a) Pyridine — Piperidine Alkaloids: Areca nut, Lobelia, Tobacco.
(b) Tropane Alkaloids: Belladonna, Hyoscyamus, Stramonium.
(c) Quinoline Alkaloids: Cinchona.
(d) Isoquinoline Alkaloids: Ipecacuanha, Opium.
(e) Indole alkaloids: Rauwolfia, catharanthus, nux vomica, physostigma, ergot.
(f) Imidazole alkaloids: Pilocarpus.
(g) Steroidal alkaloids: Veratrum.
(h) Alkaloidal amines: Ephedra, colchicum.
(i) Purine Bases: Tea, Coffee.
4. TUMOUR INHIBITORS FROM PLANT: Detailed study of various antitumour agents isolated from plants.
PHARMACOGNOSY-IV
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Isolation and separation of active constituents of crude drugs by paper and thin layer chromatography.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed., Lea and Febiger, Philadelphia, 1988.
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto, 2002.
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission Monograph Series, Islamabad, pp74, 1985.
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission, Islamabad, 1985.
8. Youngkin H W, Text Book of Pharmacognosy, The Blakiston Co, Toronto, 6th Ed., 1948.
Third Professional, Second Semester, Pharmacology
PHARMACOLOGY AND THERAPEUTICS-IV (Systemic Pharmacology-II)
(Theory)
Cr. Hr. 03
1. CHEMOTHERAPY
(a) Classification of drugs.
(b) Antimicrobials: Sulphonamides, Antivirals, Antiprotozoals (Treatment of Malaria and Treatment of Amebiasis), Antifungals, Anthelmintics, Anti-neoplastic and Immunosuppressive drugs, Drug treatment of Leprosy and Antibiotics (Penicillins, Cephalosporins, Aminoglycosides, Tetracyclines, Chloramphenicol, Macrolides, Quinolones and Miscellaneous Antibiotics).
(c) Antihypertensive Drugs.
(d) Steroids and Antisteroid drugs.
2. HORMONES, ANTAGONISTS AND OTHER AGENTS AFFECTING ENDOCRINE FUNCTION
(a) Endocrine function and dysfunctions.
(b) Drug used for therapy of Diabetes Mellitus: Insulins and Oral Hypoglycemic agents.
(c) Corticosteroids.
(d) Thyroid hormone and anti-thyroid drugs.
3. TOXICOLOGY
(a) Pollution and its typers (water, air, food).
(b) Poison and principle of treatment of poisoning.
(c) Poisoning (Sign & symptom and treatment): Ethanol, Barbiturates, Digitalis, Salicylides, Strychnine, Narcotics, Nicotine, Paracetamol, Benzodiazepines and Organophosphorous compounds.
(d) Chelating agents and their role in poisoning: Dimercaprol, Calcium disodium edentate, Pencillamine and Defroxamine.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY & THERAPEUTICS-IV (Systemic Pharmacology-II)
(Laboratory)
Cr. Hr. 01
NOTE: - Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g.
1. To identify and differentiate the effects of unknown drug on human and the nerve plexus of frog.
2. To demonstrate the effects of Acetylcholine on the Rectus abdominus muscle of frog and competitive.
3. Pharmacological antagomism by Neuromuscular blocking agent e.g. Gallamine.
4. To identify the unknown drug by performing pharmacological competitive antagonism on Rectus.
5. Abdominus muscle of Frog.
6. To study the anti-coagulant effects of Heparin and oral anti-coagulants on Rabbits.
7. To identify the unknown anti-coagulant drug using Rabbits.
8. To demonstrate the graded Dose-Response curve of Acetylcholine on Rabbit intestine.
9. To identify unknown concentration of Acetycholine from graded Dose- Response curves.
Recommended Books (Pharmacology)
1. Goodman Gillman, Pharmacological basis of therapeutics.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology,
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics,
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi,
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung, B G, Basic and Clinical Pharmacology,
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001.
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993.
10. Qayum A Fundamentals of Experimental Pharmacology.
11. Bertram G K, Basic and Clinical Pharmacology, Paramount Publishing Business & Professional Group, USA, 6th Ed., 1995.
12. William F Ganong, W F, Review of Medical physiology, Prentice Hall International Inc, New Jersey.
(Theory)
Cr. Hr. 03
1. CHEMOTHERAPY
(a) Classification of drugs.
(b) Antimicrobials: Sulphonamides, Antivirals, Antiprotozoals (Treatment of Malaria and Treatment of Amebiasis), Antifungals, Anthelmintics, Anti-neoplastic and Immunosuppressive drugs, Drug treatment of Leprosy and Antibiotics (Penicillins, Cephalosporins, Aminoglycosides, Tetracyclines, Chloramphenicol, Macrolides, Quinolones and Miscellaneous Antibiotics).
(c) Antihypertensive Drugs.
(d) Steroids and Antisteroid drugs.
2. HORMONES, ANTAGONISTS AND OTHER AGENTS AFFECTING ENDOCRINE FUNCTION
(a) Endocrine function and dysfunctions.
(b) Drug used for therapy of Diabetes Mellitus: Insulins and Oral Hypoglycemic agents.
(c) Corticosteroids.
(d) Thyroid hormone and anti-thyroid drugs.
3. TOXICOLOGY
(a) Pollution and its typers (water, air, food).
(b) Poison and principle of treatment of poisoning.
(c) Poisoning (Sign & symptom and treatment): Ethanol, Barbiturates, Digitalis, Salicylides, Strychnine, Narcotics, Nicotine, Paracetamol, Benzodiazepines and Organophosphorous compounds.
(d) Chelating agents and their role in poisoning: Dimercaprol, Calcium disodium edentate, Pencillamine and Defroxamine.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY & THERAPEUTICS-IV (Systemic Pharmacology-II)
(Laboratory)
Cr. Hr. 01
NOTE: - Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g.
1. To identify and differentiate the effects of unknown drug on human and the nerve plexus of frog.
2. To demonstrate the effects of Acetylcholine on the Rectus abdominus muscle of frog and competitive.
3. Pharmacological antagomism by Neuromuscular blocking agent e.g. Gallamine.
4. To identify the unknown drug by performing pharmacological competitive antagonism on Rectus.
5. Abdominus muscle of Frog.
6. To study the anti-coagulant effects of Heparin and oral anti-coagulants on Rabbits.
7. To identify the unknown anti-coagulant drug using Rabbits.
8. To demonstrate the graded Dose-Response curve of Acetylcholine on Rabbit intestine.
9. To identify unknown concentration of Acetycholine from graded Dose- Response curves.
Recommended Books (Pharmacology)
1. Goodman Gillman, Pharmacological basis of therapeutics.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology,
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics,
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi,
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung, B G, Basic and Clinical Pharmacology,
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001.
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993.
10. Qayum A Fundamentals of Experimental Pharmacology.
11. Bertram G K, Basic and Clinical Pharmacology, Paramount Publishing Business & Professional Group, USA, 6th Ed., 1995.
12. William F Ganong, W F, Review of Medical physiology, Prentice Hall International Inc, New Jersey.
Third Professional, Second Semester, Computer
COMPUTER AND ITS APPLICATIONS IN PHARMACY
(Theory)
Cr. Hr. 03
1. Fundamentals basic concept of computers History of Data Processing, Types of Computers, Components of a Computer, Computer System and Business Computer System, Backing Storage Devices, Unit of Memory, Viruses and Anti-viruses Issues.
2. System Analysis and Design what is a System? Steps in system life cycle, Data Gathering and Data Analysis, Designing a New System, Development and Implementation of New System, Documentation.
3. Data Processing Data Processing, The Data Processing Cycle, The Collection and Computing of data, Manual collection of data, The main methods of data input, Devices used to collect data, Data Verification, Data Validation, Output and Recording of data, Types of data processing systems, Types of Computer Operation, Batch Processing and Real-time Processing.
4. Data Communication Applications of Data Communication, Components of a data communication system, Rate of data Transmission, Computer Networks, Network Topology, Gateway, E-mail/Internet concepts.
COMPUTER AND ITS APPLICATIONS IN PHARMACY
(Laboratory)
Cr. Hr. 01
1. Internet and E-mail: Internet and Microsoft Internet Explorer 5, Addresses, Links and Downloading, Searching the Internet, E-mail and Newsgroups, Favorites, security and Customizing Explorer.
2. Web Page Development: Introduction to Front-page, Creating a First Web site, Basic
Formatting Techniques, Manipulating Tables within Front-page, Front-page, Picture and Multimedia, Hyper linking, Bookmarks and Image Maps, Introducing Front-page “components”, Front-page and Frames, Managing your Web, Good site design, Publishing and publicizing.
3. Complete Statistical Package like SPSS.
4. Languages
At least two prevailing languages will be taught.
Recommended Books
1. Elias M System Analysis. Award Galgotia Publications, New Delhi, 1989.
2. Peter Norton, Inside IBM PC. Brady Computer Books, New York, 1988.
3. Dennis N, MS-DOS. Jump Practice Hall Press, New York, 1987.
4. Peter Norton, PC-DOS. Brady Computer Books, New York, 1985.
(Theory)
Cr. Hr. 03
1. Fundamentals basic concept of computers History of Data Processing, Types of Computers, Components of a Computer, Computer System and Business Computer System, Backing Storage Devices, Unit of Memory, Viruses and Anti-viruses Issues.
2. System Analysis and Design what is a System? Steps in system life cycle, Data Gathering and Data Analysis, Designing a New System, Development and Implementation of New System, Documentation.
3. Data Processing Data Processing, The Data Processing Cycle, The Collection and Computing of data, Manual collection of data, The main methods of data input, Devices used to collect data, Data Verification, Data Validation, Output and Recording of data, Types of data processing systems, Types of Computer Operation, Batch Processing and Real-time Processing.
4. Data Communication Applications of Data Communication, Components of a data communication system, Rate of data Transmission, Computer Networks, Network Topology, Gateway, E-mail/Internet concepts.
COMPUTER AND ITS APPLICATIONS IN PHARMACY
(Laboratory)
Cr. Hr. 01
1. Internet and E-mail: Internet and Microsoft Internet Explorer 5, Addresses, Links and Downloading, Searching the Internet, E-mail and Newsgroups, Favorites, security and Customizing Explorer.
2. Web Page Development: Introduction to Front-page, Creating a First Web site, Basic
Formatting Techniques, Manipulating Tables within Front-page, Front-page, Picture and Multimedia, Hyper linking, Bookmarks and Image Maps, Introducing Front-page “components”, Front-page and Frames, Managing your Web, Good site design, Publishing and publicizing.
3. Complete Statistical Package like SPSS.
4. Languages
At least two prevailing languages will be taught.
Recommended Books
1. Elias M System Analysis. Award Galgotia Publications, New Delhi, 1989.
2. Peter Norton, Inside IBM PC. Brady Computer Books, New York, 1988.
3. Dennis N, MS-DOS. Jump Practice Hall Press, New York, 1987.
4. Peter Norton, PC-DOS. Brady Computer Books, New York, 1985.
Third Professional, First Semester, Pharmaceutics
PHARMACEUTICS-V (Dispensing Pharmacy)
(Theory)
Cr. Hr. 02
1. Basic Principles of Compounding and Dispensing Including: Weights and Measures, Calculations for compounding and Dispensing, Fundamental operations in Compounding, Containers and closures for Dispensed Products, Prescription-Handling (Parts of Prescription, Filling, Interpretation, Pricing) and Labelling of Dispensed Medication.
2. Extemporaneous Dispensing of: Solutions, Suspensions, Emulsions, Creams, Ointments, Pastes and gels, Suppositories and pessaries, Powders and granules and Oral unit dosage form.
3. Pharmaceutical Incompatibilities: Types of Incompatibilities, Manifestations, Correction and Prevention with reference to typical examples.
4. Classical dosage Forms.
5. I.V. Admixtures.
6. Radio-Pharmacy-Techniques and Applications.
PHARMACEUTICS-V (Dispensing Pharmacy)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Practical introduction to prescription-handling, interpretation, filling and Labeling.
1. Mixtures: Dispensing of simple mixtures containing soluble substances only, mixtures containing diffusable substances, indiffusable substances and mixtures forming precipitate.
2. Powders: Dispensing of simple powders, compound powders and effervescent powders for external use.
3. Incompatibility: Practical Importance of Incompatibilities.
4. Ointments And Creams: Dispensing of iodine and Methyl Salicylate ointment. Dispensing of cold cream and vanishing creams.
5. Cosmetics: Lipstic, talcum powder, after shave lotion, shaving cream. (Note: A minimum of 20 practicals will be conducted)
Recommended Books
1. Cooper and Guns, Dispensing, CBS Publishers & Distributors, New Delhi, 1986.
2. Hussa’s Dispensing.
3. Remington’s Pharmaceutical Sciences, Mack Publishing Company, USA, 2001.
4. Martindale's Extra Pharmacopoeia.
(Theory)
Cr. Hr. 02
1. Basic Principles of Compounding and Dispensing Including: Weights and Measures, Calculations for compounding and Dispensing, Fundamental operations in Compounding, Containers and closures for Dispensed Products, Prescription-Handling (Parts of Prescription, Filling, Interpretation, Pricing) and Labelling of Dispensed Medication.
2. Extemporaneous Dispensing of: Solutions, Suspensions, Emulsions, Creams, Ointments, Pastes and gels, Suppositories and pessaries, Powders and granules and Oral unit dosage form.
3. Pharmaceutical Incompatibilities: Types of Incompatibilities, Manifestations, Correction and Prevention with reference to typical examples.
4. Classical dosage Forms.
5. I.V. Admixtures.
6. Radio-Pharmacy-Techniques and Applications.
PHARMACEUTICS-V (Dispensing Pharmacy)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Practical introduction to prescription-handling, interpretation, filling and Labeling.
1. Mixtures: Dispensing of simple mixtures containing soluble substances only, mixtures containing diffusable substances, indiffusable substances and mixtures forming precipitate.
2. Powders: Dispensing of simple powders, compound powders and effervescent powders for external use.
3. Incompatibility: Practical Importance of Incompatibilities.
4. Ointments And Creams: Dispensing of iodine and Methyl Salicylate ointment. Dispensing of cold cream and vanishing creams.
5. Cosmetics: Lipstic, talcum powder, after shave lotion, shaving cream. (Note: A minimum of 20 practicals will be conducted)
Recommended Books
1. Cooper and Guns, Dispensing, CBS Publishers & Distributors, New Delhi, 1986.
2. Hussa’s Dispensing.
3. Remington’s Pharmaceutical Sciences, Mack Publishing Company, USA, 2001.
4. Martindale's Extra Pharmacopoeia.
Third Professional, First semester, Pharmaceutical Chemistry
PHARMACEUTICAL CHEMISTRY-III (Instrumentation-I)
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
Theory, Instrumentation and Pharmaceutical Applications of the following Spectroscopic Methods
1. Atomic Absorption and Emission Spectroscopy.
2. Molecular fluorescence spectroscopy.
3. Flame Photometry.
4. I.R. Spectroscopy.
5. Mass Spectroscopy.
6. NMR Spectroscopy.
7. UV/Visible Spectroscopy.
PHARMACEUTICAL CHEMISTRY-III (Instrumentation-I)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the requirements, e.g. Determination of the Purity and Composition of the unknown drugs by using at least each of the above techniques.
Recommended Books
1. Lough W J, High Performance Liquid Chromatography, Blacki Academic Press, New York, 1996.
2. William Kemp,Organic Spectroscopy, Ellsi Horwood, London, 1990.
3. M Aminuddin & Javed Iqbal, Theory and Practice of Chromatography, University Grants Commission, Islamabad-Pakistan (2000).
4. A H Beckett and J B Stennlake, Practical Pharmaceutical Chemistry, Part I and II, the Aulton Press, London.
5. A M Knevel and F E Digangi, Jenkins’s quantitative Pharmaceutical Chemistry, McGraw-Hill Book Company, New York.
6. Braithwaite and F J Smith, Chromatographic Methods, Chapman and Hall, London.
7. E Heftmann, Chromatography, Von Nostrond Reinheld Co, New York, 1975.
8. Pryde and M J Gilbert, Applications of High Performance Liquid Chromatography, Chapman & Hall, London, 1979.
9. E Stahl, Thin Layer Chromatography, Springer-Verlag, Berlin, 1969.
10. R Hamilton, Introduction to HPLC, P A Sewell, Chapman & Hall, London, 1982
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
Theory, Instrumentation and Pharmaceutical Applications of the following Spectroscopic Methods
1. Atomic Absorption and Emission Spectroscopy.
2. Molecular fluorescence spectroscopy.
3. Flame Photometry.
4. I.R. Spectroscopy.
5. Mass Spectroscopy.
6. NMR Spectroscopy.
7. UV/Visible Spectroscopy.
PHARMACEUTICAL CHEMISTRY-III (Instrumentation-I)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the requirements, e.g. Determination of the Purity and Composition of the unknown drugs by using at least each of the above techniques.
Recommended Books
1. Lough W J, High Performance Liquid Chromatography, Blacki Academic Press, New York, 1996.
2. William Kemp,Organic Spectroscopy, Ellsi Horwood, London, 1990.
3. M Aminuddin & Javed Iqbal, Theory and Practice of Chromatography, University Grants Commission, Islamabad-Pakistan (2000).
4. A H Beckett and J B Stennlake, Practical Pharmaceutical Chemistry, Part I and II, the Aulton Press, London.
5. A M Knevel and F E Digangi, Jenkins’s quantitative Pharmaceutical Chemistry, McGraw-Hill Book Company, New York.
6. Braithwaite and F J Smith, Chromatographic Methods, Chapman and Hall, London.
7. E Heftmann, Chromatography, Von Nostrond Reinheld Co, New York, 1975.
8. Pryde and M J Gilbert, Applications of High Performance Liquid Chromatography, Chapman & Hall, London, 1979.
9. E Stahl, Thin Layer Chromatography, Springer-Verlag, Berlin, 1969.
10. R Hamilton, Introduction to HPLC, P A Sewell, Chapman & Hall, London, 1982
Third Professional, First semester, Pharmacognosy
PHARMACOGNOSY-III
(Theory)
Cr. Hr. 03
1. SEPARATION AND ISOLATION OF PLANT CONSTITUTIONS: An introduction to chromatography and chromatographic techniques e.g. Adsorption Chromatography and Partition Chromatography.
2. CARBOHYDRATES: Introduction of carbohydrate.
(a) Sucrose and Sucrose containing drugs: Sucrose, Dextrose, Liquid glucose, Fructose, Lactose, Xylose, Caramel, Honey, Starch, Inulin, Dextrine etc.
(b) Cellulose and Cellulose Derivatives: Purified cotton, Powdered cellulose, Microcrystalline cellulose, Methyl cellulose, Sodium Carboxy-methyl cellulose.
(c) Gums and Mucilages: Tragacenth, Acacia, Sodium Alginate, Agar, Pectin.
3. GLYCOSIDES: Introduction, classification, chemistry and medicinal uses of:
(a) Cardioactive glycosides: Digitalis, Strophanthus and white squill.
(b) Anthroquinone glycosides: Cascara, Aloe, Rhubarb, Cochineal and Senna.
(c) Saponin glycosides: Glycyrrhiza, Sarsaparilla.
(d) Cyanophore glycosides: Wild cherry.
(e) Isothiocyanate glycosides: Black Mustard.
(f) Lactone glycosides: Cantharide.
(g) Aldehyde glycosides: Vanilla.
(h) Miscellaneous glycosides: Gentian,. Quassia, Dioscorea.
4. TANNINS: Introduction, classification, properties and chemical identity tests of Tannins and Tannin containing compounds. Detailed study of Hammamelis, Catechu and Nut Galls.
5. LIPIDS: Introduction. Detailed study of:
(a) Fixed Oils: Castor oil, cotton seed oil, olive oil, peanut oil, sun flower oil, corn oil, coconut oil, Almond oil, Linseed oil, Mustard oil, Sesame oil and soybean oil.
(b) Fats and Related Compounds: Theobroma oil and Lenolin.
(c) Waxes: Bees wax, carnauba wax, spermaceti and Jojoba oil.
PHARMACOGNOSY-III
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Extraction of the active constituents of crude drugs and chemical tests for their identification.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed.,
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto,
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission .
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors,
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission,
8. Youngkin H W, Text Book of Pharmacognosy. The Blakiston Co. Toronto, 6th Ed.,
(Theory)
Cr. Hr. 03
1. SEPARATION AND ISOLATION OF PLANT CONSTITUTIONS: An introduction to chromatography and chromatographic techniques e.g. Adsorption Chromatography and Partition Chromatography.
2. CARBOHYDRATES: Introduction of carbohydrate.
(a) Sucrose and Sucrose containing drugs: Sucrose, Dextrose, Liquid glucose, Fructose, Lactose, Xylose, Caramel, Honey, Starch, Inulin, Dextrine etc.
(b) Cellulose and Cellulose Derivatives: Purified cotton, Powdered cellulose, Microcrystalline cellulose, Methyl cellulose, Sodium Carboxy-methyl cellulose.
(c) Gums and Mucilages: Tragacenth, Acacia, Sodium Alginate, Agar, Pectin.
3. GLYCOSIDES: Introduction, classification, chemistry and medicinal uses of:
(a) Cardioactive glycosides: Digitalis, Strophanthus and white squill.
(b) Anthroquinone glycosides: Cascara, Aloe, Rhubarb, Cochineal and Senna.
(c) Saponin glycosides: Glycyrrhiza, Sarsaparilla.
(d) Cyanophore glycosides: Wild cherry.
(e) Isothiocyanate glycosides: Black Mustard.
(f) Lactone glycosides: Cantharide.
(g) Aldehyde glycosides: Vanilla.
(h) Miscellaneous glycosides: Gentian,. Quassia, Dioscorea.
4. TANNINS: Introduction, classification, properties and chemical identity tests of Tannins and Tannin containing compounds. Detailed study of Hammamelis, Catechu and Nut Galls.
5. LIPIDS: Introduction. Detailed study of:
(a) Fixed Oils: Castor oil, cotton seed oil, olive oil, peanut oil, sun flower oil, corn oil, coconut oil, Almond oil, Linseed oil, Mustard oil, Sesame oil and soybean oil.
(b) Fats and Related Compounds: Theobroma oil and Lenolin.
(c) Waxes: Bees wax, carnauba wax, spermaceti and Jojoba oil.
PHARMACOGNOSY-III
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Extraction of the active constituents of crude drugs and chemical tests for their identification.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed.,
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto,
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission .
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors,
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission,
8. Youngkin H W, Text Book of Pharmacognosy. The Blakiston Co. Toronto, 6th Ed.,
Third Professional, First Semester,Pharmacology
PHARMACOLOGY & THERAPEUTICS (Systemic Pharmacology)
(Theory)
Cr. Hr. 03
1. DRUGS ACTING ON CENTRAL NERVOUS SYSTEM
(a) CNS – Depressants: Hypnotic & Sedatives and Analgesics (Narcotic Analgesics and opioid antagonists, Analgesic, Antipyretic and Anti-inflammatory drugs [NSAID] including
Disease-modifying antirheumatic drugs and Drug treatment of Gout)
(b) CNS – Stimulants: Cerebral Stimulants, Medullary stimulants, Spinal Cord Stimulants, Antidepressants, Psychotomimetic or Hallucinogenics, Psychotherapeutic Agents (Anxiolytics and Antipsychotics), Drug treatment of Epilepsy and Drug treatment of Parkinsonism and other movement disorders.
2. ANAESTHETICS
(a) Anaesthesia and its clinical importance.
(b) General Anaesthesia, Mechanism of action and its application.
(c) General Anaesthetics.
(d) Local Anaesthetics.
(e) Spinal Anaesthesia and drug used.
(f) Techniques of Local Anaesthesia.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY & THERAPEUTICS (Systemic Pharmacology)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. To study the convulsant effects of strychnine and picrotoxin in frogs and to determine the site of action. To identify the unknown (convulsant) drug and determine its site of action. To study the effects of Adrenaline on Human Eyes. To study the effects of Pilocarpine on Human Eyes. To study the effect of Homatropine on Human Eyes. To identify and observe the effects of unknown drugs on Human Eyes. To study the effects of local anaesthetic drugs on human and the nerve plexus of frog.
Recommended Books
1. Goodman Gillman, Pharmacological basis of therapeutics.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology, Oxford University Press, New York, 1995.
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics,
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi,
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung, B G, Basic and Clinical Pharmacology,
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001.
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993.
10. Prof Dr A Qayum, Fundamentals of Experimental Pharmacology.
11. Bertram G K, Basic and Clinical Pharmacology
12. William F Ganong, W F, Review of Medical physiology
(Theory)
Cr. Hr. 03
1. DRUGS ACTING ON CENTRAL NERVOUS SYSTEM
(a) CNS – Depressants: Hypnotic & Sedatives and Analgesics (Narcotic Analgesics and opioid antagonists, Analgesic, Antipyretic and Anti-inflammatory drugs [NSAID] including
Disease-modifying antirheumatic drugs and Drug treatment of Gout)
(b) CNS – Stimulants: Cerebral Stimulants, Medullary stimulants, Spinal Cord Stimulants, Antidepressants, Psychotomimetic or Hallucinogenics, Psychotherapeutic Agents (Anxiolytics and Antipsychotics), Drug treatment of Epilepsy and Drug treatment of Parkinsonism and other movement disorders.
2. ANAESTHETICS
(a) Anaesthesia and its clinical importance.
(b) General Anaesthesia, Mechanism of action and its application.
(c) General Anaesthetics.
(d) Local Anaesthetics.
(e) Spinal Anaesthesia and drug used.
(f) Techniques of Local Anaesthesia.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY & THERAPEUTICS (Systemic Pharmacology)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. To study the convulsant effects of strychnine and picrotoxin in frogs and to determine the site of action. To identify the unknown (convulsant) drug and determine its site of action. To study the effects of Adrenaline on Human Eyes. To study the effects of Pilocarpine on Human Eyes. To study the effect of Homatropine on Human Eyes. To identify and observe the effects of unknown drugs on Human Eyes. To study the effects of local anaesthetic drugs on human and the nerve plexus of frog.
Recommended Books
1. Goodman Gillman, Pharmacological basis of therapeutics.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology, Oxford University Press, New York, 1995.
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics,
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi,
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung, B G, Basic and Clinical Pharmacology,
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001.
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993.
10. Prof Dr A Qayum, Fundamentals of Experimental Pharmacology.
11. Bertram G K, Basic and Clinical Pharmacology
12. William F Ganong, W F, Review of Medical physiology
Third Professional, First Semester, Pathology
PATHOLOGY
(Theory)
Cr. Hr. 03
1. SCOPE OF PATHOLOGY and; CONCEPT OF DISEASES:
2. DEFINITION AND TERMINOLOGY: Ischemia, Hypoxia, Necrosis, Infarction, Atrophy, Hypertrophy, Hyperplasia, Metaplasia, Aplasia, Anaplasia.
3. RESPONSE OF BODY TO INJURY AND INFECTION: Acuate inflammation, Chronic inflammation, Immunity, Allergy, Hyper Sensitivity.
4. SPECIFIC: Ulcer (Peptic, Doudenal), Hypertension, Leukemia or Blood Cancer (Malignant Carcinoma, Sarcoma & Lymphomas), Diagnosis and treatment of Cancer in general, fate, survival and prognosis with tumors.
PATHOLOGY
(Laboratory)
Cr. Hr. 01
Study of Pathological Slides of various Pathological Conditions
Acute inflammation, Chronic inflammation, Chronic specific inflammation, Different types of Degeneration, Thrombosis, Embolism, Infarction, Necrosis, Gangrene, Hyperplasia, Metaplasia, Pigmentation, Calcification, CVC, Papilloma, Adenoma, Chondroma, Fibroma, Leomyoma, Neofibroma, Sq. Cell Carcinoma, Basal Cell Carcinoma, Transitional Cell Carcinoma, Adenocarcinoma, Fibrocarcinoma, Rhadomyosarcoma, Leomyosarcoma, Lymphosarcoma, Liposarcoma, Reticular Cell Sarcoma, Hodgkins disease, Breast Carcinoma, Osteogenic Sarcoma, Osteoclastoma.
Examiantion of different body fluids in various Pathological Conditions
Urine complete Examination, stool Examination, Blood Complete Examination, Semen Examination, Cerebrospinal Fluid Examination, Pericardial fluid examination, Pleural Fluid Examination, Ascitic Fluid Examination, Blood Sugar, Blood Urea, Blood Choleterol etc.
Tests for various Specimens of Clinical Importance
Techniques of Clinical Blood Examination for various disases, Gastric Analysis, Tests for liver function test, Renal function test, Tests for endocrine abnormalities, Biopsies and cytologic techniques.
Recommended Books
1. Kumar Cotran Robins, Basic Pathology, 6th Ed., W B Saunders Company, Philadelphia (1992).
2. Walters and Israel, General Pathology, Churchill Livingstone, London (1998).
3. Peter S Macfarlane, Robin Reid, Robin Collander, Pathology Illustrated, Churchill Livingstone, London (1998).
4. Robbins Pathology, W B Saunders Co, London, 2nd Ed., 1962.
5. Walter G B, General Pathology, Churchill Livingstone, New York, 1996.
(Theory)
Cr. Hr. 03
1. SCOPE OF PATHOLOGY and; CONCEPT OF DISEASES:
2. DEFINITION AND TERMINOLOGY: Ischemia, Hypoxia, Necrosis, Infarction, Atrophy, Hypertrophy, Hyperplasia, Metaplasia, Aplasia, Anaplasia.
3. RESPONSE OF BODY TO INJURY AND INFECTION: Acuate inflammation, Chronic inflammation, Immunity, Allergy, Hyper Sensitivity.
4. SPECIFIC: Ulcer (Peptic, Doudenal), Hypertension, Leukemia or Blood Cancer (Malignant Carcinoma, Sarcoma & Lymphomas), Diagnosis and treatment of Cancer in general, fate, survival and prognosis with tumors.
PATHOLOGY
(Laboratory)
Cr. Hr. 01
Study of Pathological Slides of various Pathological Conditions
Acute inflammation, Chronic inflammation, Chronic specific inflammation, Different types of Degeneration, Thrombosis, Embolism, Infarction, Necrosis, Gangrene, Hyperplasia, Metaplasia, Pigmentation, Calcification, CVC, Papilloma, Adenoma, Chondroma, Fibroma, Leomyoma, Neofibroma, Sq. Cell Carcinoma, Basal Cell Carcinoma, Transitional Cell Carcinoma, Adenocarcinoma, Fibrocarcinoma, Rhadomyosarcoma, Leomyosarcoma, Lymphosarcoma, Liposarcoma, Reticular Cell Sarcoma, Hodgkins disease, Breast Carcinoma, Osteogenic Sarcoma, Osteoclastoma.
Examiantion of different body fluids in various Pathological Conditions
Urine complete Examination, stool Examination, Blood Complete Examination, Semen Examination, Cerebrospinal Fluid Examination, Pericardial fluid examination, Pleural Fluid Examination, Ascitic Fluid Examination, Blood Sugar, Blood Urea, Blood Choleterol etc.
Tests for various Specimens of Clinical Importance
Techniques of Clinical Blood Examination for various disases, Gastric Analysis, Tests for liver function test, Renal function test, Tests for endocrine abnormalities, Biopsies and cytologic techniques.
Recommended Books
1. Kumar Cotran Robins, Basic Pathology, 6th Ed., W B Saunders Company, Philadelphia (1992).
2. Walters and Israel, General Pathology, Churchill Livingstone, London (1998).
3. Peter S Macfarlane, Robin Reid, Robin Collander, Pathology Illustrated, Churchill Livingstone, London (1998).
4. Robbins Pathology, W B Saunders Co, London, 2nd Ed., 1962.
5. Walter G B, General Pathology, Churchill Livingstone, New York, 1996.
Wednesday, March 2, 2011
Second Professional, Second Semester, Islamiyat
ISLAMIYAT
(Theory)
Cr. Hr. 03
As per syllabi of B.A/B.Sc. classes, approved by the respective University
(Theory)
Cr. Hr. 03
As per syllabi of B.A/B.Sc. classes, approved by the respective University
Second Professional, Second Semester, Microbiology
PHARMACEUTICAL MICROBIOLOGY-II
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
2. INDUSTRIAL MICROBIOLOGY: Introduction to Sterilization/Disinfection. Fermentation. Pharmaceutical products produced by fermentation process (Penicillins, Cepalosporins, Gentamycin, Erythromycin, Tetracyclines, Rifamycin, Griseofulvin)
3. IMMUNOLOGY: Introduction, Types of Imunity: Specific and nonspecific (Cellular basis of Immune response. Immunity, autoimmunity, tolerance. Antigen. Antibodies). Antigen-Antibody reactions and their clinical and diagnostic applications. Hypersensitivity and allergy. Drug allergy mechanism. Vaccination: Introduction and aims. Types of Vaccines. Current vaccine practices.
4. FACTORY AND HOSPITAL HYGIENE AND GOOD MANUFACTURING PRACTICE: Introduction, Control of Microbial contamination during manufacture, Mnaufacture of Sterile products, A Guide to Current Good Pharmaceutical Manufacturing Practices.
PHARMACEUTICAL MICROBIOLOGY-II
(LABORATORY)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Sterilization of Glassware and pharmaceutical products by various methods. Microbiological assays of: Antibiotics and vitamins.
Recommended Books
1. Jawetiz, Medical Microbiology and Immunology, 5th Ed., Churchill Livingstone, London, 1998.
2. W B Hugo & A D Russell, Pharmaceutical Microbiology, Black Well Science Ltd, London, 6th Ed., 1998.
3. Lippincot, Microbiology by lipponcott, William & Willkin, USA, 2001.
4. Alcamo, Introduction to Microbiology, John Bartlett Publishers, 6th Ed., 2003.
5. Collin and Lynes, Microbiological Methods, Vutterworth Heineman, Oxford, 1995.
6. M Mekallee, Microbiology: Essentials and Application, McGraw-Hill Inc, 2nd Ed.
7. Singleton and Sainsbury, Dictionary of Microbiology and Molecular biology, John Willey & Sons, New York, 2000.
8. Pelczar, Microbiology, McGraw-Hill Inc, 1996.
9. Prescott, Harley, Microbiology, 2nd Ed., Klein Wm C Brown Publishers, 2001.
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
2. INDUSTRIAL MICROBIOLOGY: Introduction to Sterilization/Disinfection. Fermentation. Pharmaceutical products produced by fermentation process (Penicillins, Cepalosporins, Gentamycin, Erythromycin, Tetracyclines, Rifamycin, Griseofulvin)
3. IMMUNOLOGY: Introduction, Types of Imunity: Specific and nonspecific (Cellular basis of Immune response. Immunity, autoimmunity, tolerance. Antigen. Antibodies). Antigen-Antibody reactions and their clinical and diagnostic applications. Hypersensitivity and allergy. Drug allergy mechanism. Vaccination: Introduction and aims. Types of Vaccines. Current vaccine practices.
4. FACTORY AND HOSPITAL HYGIENE AND GOOD MANUFACTURING PRACTICE: Introduction, Control of Microbial contamination during manufacture, Mnaufacture of Sterile products, A Guide to Current Good Pharmaceutical Manufacturing Practices.
PHARMACEUTICAL MICROBIOLOGY-II
(LABORATORY)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Sterilization of Glassware and pharmaceutical products by various methods. Microbiological assays of: Antibiotics and vitamins.
Recommended Books
1. Jawetiz, Medical Microbiology and Immunology, 5th Ed., Churchill Livingstone, London, 1998.
2. W B Hugo & A D Russell, Pharmaceutical Microbiology, Black Well Science Ltd, London, 6th Ed., 1998.
3. Lippincot, Microbiology by lipponcott, William & Willkin, USA, 2001.
4. Alcamo, Introduction to Microbiology, John Bartlett Publishers, 6th Ed., 2003.
5. Collin and Lynes, Microbiological Methods, Vutterworth Heineman, Oxford, 1995.
6. M Mekallee, Microbiology: Essentials and Application, McGraw-Hill Inc, 2nd Ed.
7. Singleton and Sainsbury, Dictionary of Microbiology and Molecular biology, John Willey & Sons, New York, 2000.
8. Pelczar, Microbiology, McGraw-Hill Inc, 1996.
9. Prescott, Harley, Microbiology, 2nd Ed., Klein Wm C Brown Publishers, 2001.
Second Professional, Second Semester, Pharmacognosy
PHARMACOGNOSY-II
(Theory)
Cr. Hr. 03
1. ALLERGENS AND ALLERGENIC PREPARATION: Introduction, case history, skin test, treatment off allergy, inhalant, ingestant, injectant, contactant, infectant and infestant allergens. Mechanism of allergy.
2. ENZYMES: Enzymes obtained from plant source. (Phytoenzymes). Papain Bromelain and Malt Extract. Enzymes obtained from Animal source. Rennin pepsin, Pancreatin and Pancrealipase.
3. POISONOUS PLANTS: General introduction of poisonous plants with special reference to Pakistan.
4. PESTICIDES: Introduction. Methods of controlling pests with special reference to natural methods.
PHARMACOGNOSY-II
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Microscopic examination of powders and sections of plant drugs. A Study Tour will be an integral part of the syllabus and will be arranged at the end of the session for collection of medicinal plants from various hilly areas of the country.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed., Lea and Febiger, Philadelphia, 1988.
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto, 2002.
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission Monograph Series, Islamabad, pp74, 1985.
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission, Islamabad, 1985.
8. Youngkin H W, Text Book of Pharmacognosy, The Blakiston Co, Toronto, 6th Ed., 1948.
(Theory)
Cr. Hr. 03
1. ALLERGENS AND ALLERGENIC PREPARATION: Introduction, case history, skin test, treatment off allergy, inhalant, ingestant, injectant, contactant, infectant and infestant allergens. Mechanism of allergy.
2. ENZYMES: Enzymes obtained from plant source. (Phytoenzymes). Papain Bromelain and Malt Extract. Enzymes obtained from Animal source. Rennin pepsin, Pancreatin and Pancrealipase.
3. POISONOUS PLANTS: General introduction of poisonous plants with special reference to Pakistan.
4. PESTICIDES: Introduction. Methods of controlling pests with special reference to natural methods.
PHARMACOGNOSY-II
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Microscopic examination of powders and sections of plant drugs. A Study Tour will be an integral part of the syllabus and will be arranged at the end of the session for collection of medicinal plants from various hilly areas of the country.
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed., Lea and Febiger, Philadelphia, 1988.
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto, 2002.
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission Monograph Series, Islamabad, pp74, 1985.
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission, Islamabad, 1985.
8. Youngkin H W, Text Book of Pharmacognosy, The Blakiston Co, Toronto, 6th Ed., 1948.
Second Professional, Second Semester, Pharmacology
PHARMACOLOGY and; THERAPEUTICS-II (General-II)
(Theory)
Cr. Hr. 03
1. AUTACOIDS AND THEIR ANTAGONISTS:
Histamine and Antihistamines, Serotonin and Serotonin Antagonists and Other Autocoids
2. DRUGS ACTING ON RESPIRATORY SYSTEM:
(a) Drugs used for cough (Antitussives, Expectorants and Mucolytic Agents).
(b) Drug treatment of Bronchial Asthma (Bronchodilators, Cromoglycate, Nedocromil, Cortecosteroids & other Anti-inflammatory drugs and Muscarinic receptor antagonists)
3. DRUGS ACTING ON CARDIO-VESCULAR SYSTEM:
(a) Angina pectoris and its drug treatment.
(b) Congestive heart failure & its treatment.
(c) Antiarrhythmic drugs.
(d) Agents used in Hyperlipidemia.
(e) Coagulants and Anticoagulants.
(f) Antihypertensives.
(g) Diuretics.
4. DRUGS ACTING ON GENITOURINARY SYSTEM:
Oxytoxic drugs, Ergot alkaloids and uterine relaxants.
5. ANTI-ANAEMIC DRUGS.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY & THERAPEUTICS-II (General-II)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. To demonstate the effects of vasconstrictor drugs on Frog’s blood vessels. To demonstrate the effects of stimulant drugs on Rabbit’s intestine (Acetyl choline, Barium chloride). To demonstrate the effects of depressant drugs on Rabbit’s intestine (Atropine). To differentiate the effects of an unknown drug on Rabbit’s intestine and identify the (unknown) drug. To study the effects of Adrenaline on Rabbit’s Eyes. To study the effects of Homatropine on Rabbit’s Eyes. To study the effects of Pilocarpine on Rabbit’s Eyes. To study the effects of Local Anaesthetic drug (e.g. Cocaine) on Rabbit’s Eyes. To identify the unknown drug & differentiate its effects on Rabbit’s Eyes. (Note: A minimum of 10 practicals will be conducted)
Recommended Books (Pharmacology)
1. Goodman Gillman, Pharmacological basis of therapeutics. McGraw-Hill Book Company, New York, 1996.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology, Oxford University Press, New York, 1995
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics, Popular Prakashan, Bomby, 1993.
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi, 4th Ed., 2000.
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung B G, Basic and Clinical Pharmacology, McGraw-Hill Medical Publishers, New York, 8th Ed., 2001.
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993
10. Prof Dr A Qayum, Fundamentals of Experimental Pharmacology.
11. Bertram G K, Basic and Clinical Pharmacology, Paramount Publishing Business & Professional Group, USA, 6th Ed., 1995
12. William F Ganong, W F, Review of Medical physiology, Prentice Hall International Inc, New Jersey.
(Theory)
Cr. Hr. 03
1. AUTACOIDS AND THEIR ANTAGONISTS:
Histamine and Antihistamines, Serotonin and Serotonin Antagonists and Other Autocoids
2. DRUGS ACTING ON RESPIRATORY SYSTEM:
(a) Drugs used for cough (Antitussives, Expectorants and Mucolytic Agents).
(b) Drug treatment of Bronchial Asthma (Bronchodilators, Cromoglycate, Nedocromil, Cortecosteroids & other Anti-inflammatory drugs and Muscarinic receptor antagonists)
3. DRUGS ACTING ON CARDIO-VESCULAR SYSTEM:
(a) Angina pectoris and its drug treatment.
(b) Congestive heart failure & its treatment.
(c) Antiarrhythmic drugs.
(d) Agents used in Hyperlipidemia.
(e) Coagulants and Anticoagulants.
(f) Antihypertensives.
(g) Diuretics.
4. DRUGS ACTING ON GENITOURINARY SYSTEM:
Oxytoxic drugs, Ergot alkaloids and uterine relaxants.
5. ANTI-ANAEMIC DRUGS.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY & THERAPEUTICS-II (General-II)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. To demonstate the effects of vasconstrictor drugs on Frog’s blood vessels. To demonstrate the effects of stimulant drugs on Rabbit’s intestine (Acetyl choline, Barium chloride). To demonstrate the effects of depressant drugs on Rabbit’s intestine (Atropine). To differentiate the effects of an unknown drug on Rabbit’s intestine and identify the (unknown) drug. To study the effects of Adrenaline on Rabbit’s Eyes. To study the effects of Homatropine on Rabbit’s Eyes. To study the effects of Pilocarpine on Rabbit’s Eyes. To study the effects of Local Anaesthetic drug (e.g. Cocaine) on Rabbit’s Eyes. To identify the unknown drug & differentiate its effects on Rabbit’s Eyes. (Note: A minimum of 10 practicals will be conducted)
Recommended Books (Pharmacology)
1. Goodman Gillman, Pharmacological basis of therapeutics. McGraw-Hill Book Company, New York, 1996.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology, Oxford University Press, New York, 1995
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics, Popular Prakashan, Bomby, 1993.
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi, 4th Ed., 2000.
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung B G, Basic and Clinical Pharmacology, McGraw-Hill Medical Publishers, New York, 8th Ed., 2001.
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993
10. Prof Dr A Qayum, Fundamentals of Experimental Pharmacology.
11. Bertram G K, Basic and Clinical Pharmacology, Paramount Publishing Business & Professional Group, USA, 6th Ed., 1995
12. William F Ganong, W F, Review of Medical physiology, Prentice Hall International Inc, New Jersey.
Second Professional, Second Semester, Pharmaceutics
Pharmaceutics-IV (Pharmaceutical Preparations-II)
(Theory)
Cr. Hr. 03
1. TRANSDERMAL DRUG DELIVERY SYSTEMS: Introduction of Ointments, Creams, Pastes, Poultice, Plasters, Lotions, Liniments, Topical gels, Topical Tinctures, Collodions, Topical solutions, Topical Powders, Percutaneous absorption, Transdermal systems in use.
2. OPHTHALMIC, NASAL AND OTIC PREPARATIONS: Ophthalmic solutions, suspensions, ointment, inserts, contact lens solutions. Nasal decongestant solutions, Decongestant inhalers. Ear preparations: Antiinfective, anti-inflammatory and analgesic.
3. SUPPOSITORIES AND VAGINAL SUPPOSITORIES: Semi-solid Preparations, Suppositories bases, preparation, packaging and storage, Solutions/Anemas.
4. AEROSOLS, INHALATIONS AND SPRAYS: Aerosol: Principle, container and valve assembly, Propellants, filling, testing, packaging, labeling and storage.
5. POWDERS, CAPSULES, and TABLET DOSAGE FORMS: Preparation of Powders, mixing of powders, uses and packaging of powders, granules, effervescent, granulated salts. Hard gelatin capsules, capsule sizes, preparation of filled hard gelatin capsules, soft gelatin capsules, preparation and its application. Tablets, their types, characteristics and methods of preparation.
6. INTRODUCTION TO PARENTERALS: Official types of injections, solvents and vehicles for injections, added substances.
7. A brief introduction to oral hygiene products.
Pharmaceutics-IV (Pharmaceutical Preparations-II)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Prepartion of Methyl salicylate ointment, Sulpher ointment, Calamine lotion, Iodine tincture, Preparations of oral
hygiene products, Poultice of Kaolin, Effervescent granules, Distilled Water for injections.
(A minimum of 10n practicals will be conducted)
Recommended Books
1. Michel E Aulton, Pharmaceutics, ELBS/Churchill Livingstone, London, 1998.
2. Bentley’s Book of Pharmaceutics, CBS Publishers & Distributors, New Delhi, 1986
3. Pharmaceutics, The Science of Dosage Form Design. 2nd Ed., HawCourt Publisher, 2002.
4. E A Rawlins, Berdley’s Textbook of Pharmaceutics, edited by 8th time (or recent edition) 1977. Macmillan Publishing Co Inc, New York.
5. Sprowl’s (Dittert L W; Ed.), American Pharmacy, 7th Ed., J B Lippincott Co, 1990.
(Theory)
Cr. Hr. 03
1. TRANSDERMAL DRUG DELIVERY SYSTEMS: Introduction of Ointments, Creams, Pastes, Poultice, Plasters, Lotions, Liniments, Topical gels, Topical Tinctures, Collodions, Topical solutions, Topical Powders, Percutaneous absorption, Transdermal systems in use.
2. OPHTHALMIC, NASAL AND OTIC PREPARATIONS: Ophthalmic solutions, suspensions, ointment, inserts, contact lens solutions. Nasal decongestant solutions, Decongestant inhalers. Ear preparations: Antiinfective, anti-inflammatory and analgesic.
3. SUPPOSITORIES AND VAGINAL SUPPOSITORIES: Semi-solid Preparations, Suppositories bases, preparation, packaging and storage, Solutions/Anemas.
4. AEROSOLS, INHALATIONS AND SPRAYS: Aerosol: Principle, container and valve assembly, Propellants, filling, testing, packaging, labeling and storage.
5. POWDERS, CAPSULES, and TABLET DOSAGE FORMS: Preparation of Powders, mixing of powders, uses and packaging of powders, granules, effervescent, granulated salts. Hard gelatin capsules, capsule sizes, preparation of filled hard gelatin capsules, soft gelatin capsules, preparation and its application. Tablets, their types, characteristics and methods of preparation.
6. INTRODUCTION TO PARENTERALS: Official types of injections, solvents and vehicles for injections, added substances.
7. A brief introduction to oral hygiene products.
Pharmaceutics-IV (Pharmaceutical Preparations-II)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Prepartion of Methyl salicylate ointment, Sulpher ointment, Calamine lotion, Iodine tincture, Preparations of oral
hygiene products, Poultice of Kaolin, Effervescent granules, Distilled Water for injections.
(A minimum of 10n practicals will be conducted)
Recommended Books
1. Michel E Aulton, Pharmaceutics, ELBS/Churchill Livingstone, London, 1998.
2. Bentley’s Book of Pharmaceutics, CBS Publishers & Distributors, New Delhi, 1986
3. Pharmaceutics, The Science of Dosage Form Design. 2nd Ed., HawCourt Publisher, 2002.
4. E A Rawlins, Berdley’s Textbook of Pharmaceutics, edited by 8th time (or recent edition) 1977. Macmillan Publishing Co Inc, New York.
5. Sprowl’s (Dittert L W; Ed.), American Pharmacy, 7th Ed., J B Lippincott Co, 1990.
Second Professional, First semester, Pak Studies
PAKISTAN STUDIES
(Theory)
Cr. Hr. 03
As per syllabi of B.A/B.Sc. classes, approved by the respective University.
(Theory)
Cr. Hr. 03
As per syllabi of B.A/B.Sc. classes, approved by the respective University.
Second Professional, First semester, Pharmaceutical Microbiology
PHARMACEUTICAL MICROBIOLOGY-I
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
1. GENERAL MICROBIOLOGY: Historical Introduction, Scope of Microbiology with special reference to Pharmaceutical Sciences. Nomenclature and classification of Micro-organisms.
2. ORGANISMS:
The Bacteria: General and cellular Morphology, structure and function. Classification of Bacteria. Growth curve, growth factors and growth characteristics. Nutrition, Requirements and Nutrition factors affecting growth. Culture Media, Bacterial cultures and staining Methods. The Viruses: Introduction, Classification (and detail of at least one species from every group), cultivation, and replication.
3. THE FUNGI/YEAST/MOLDS.
4. THE PROTOZOA.
5. The NORMAL FLORA: Microbiology of air, water and soil (General introduction and normal inhibitants of air, water, and soil).
PHARMACEUTICAL MICROBIOLOGY-I
(Theory)
Cr. Hr. 03
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Preparation of general and selective media and culturing of micro-organisms. Total and viable counts of microorganism. Morphological and selective biochemical characteriz-ation of some specimen. Staining of Bacteria: Gram method, Acid fast, Giemasas staining, Capsule staining, Flagella staining and Spore staining. Microbiological analysis of air, water and soil.
Recommended Books
1. Jawetiz, Medical Microbiology and Immunology, 5th Ed., Churchill Livingstone, London, 1998.
2. W B Hugo & A D Russell, Pharmaceutical Microbiology, Black Well Science Ltd, London, 6th Ed., 1998.
3. Lippincot. Microbiology by Lipponcott. William & Willkin, USA, 2001.
4. Alcamo. Introduction to Microbiology. John Bartlett Publishers, 6th Ed., 2003.
5. Collin and Lynes, Microbiological Methods, Vutterworth Heineman, Oxford, 1995.
6. M Mekallee, Microbiology: Essentials and Application, McGraw-Hill Inc, 2nd Ed.
7. Singleton and Sainsbury, Dictionary of Microbiology and Molecular biology, John Willey & Sons, New York, 2000.
8. Pelczar, Microbiology, McGraw-Hill Inc, 1996.
9. Prescott, Harley, Microbiology, 2nd Ed., Klein Wm C Brown Publishers, 2001.
(Theory)
Cr. Hr. 03
Note:- The topics will be taught with special reference to their Pharmaceutical Applications.
1. GENERAL MICROBIOLOGY: Historical Introduction, Scope of Microbiology with special reference to Pharmaceutical Sciences. Nomenclature and classification of Micro-organisms.
2. ORGANISMS:
The Bacteria: General and cellular Morphology, structure and function. Classification of Bacteria. Growth curve, growth factors and growth characteristics. Nutrition, Requirements and Nutrition factors affecting growth. Culture Media, Bacterial cultures and staining Methods. The Viruses: Introduction, Classification (and detail of at least one species from every group), cultivation, and replication.
3. THE FUNGI/YEAST/MOLDS.
4. THE PROTOZOA.
5. The NORMAL FLORA: Microbiology of air, water and soil (General introduction and normal inhibitants of air, water, and soil).
PHARMACEUTICAL MICROBIOLOGY-I
(Theory)
Cr. Hr. 03
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Preparation of general and selective media and culturing of micro-organisms. Total and viable counts of microorganism. Morphological and selective biochemical characteriz-ation of some specimen. Staining of Bacteria: Gram method, Acid fast, Giemasas staining, Capsule staining, Flagella staining and Spore staining. Microbiological analysis of air, water and soil.
Recommended Books
1. Jawetiz, Medical Microbiology and Immunology, 5th Ed., Churchill Livingstone, London, 1998.
2. W B Hugo & A D Russell, Pharmaceutical Microbiology, Black Well Science Ltd, London, 6th Ed., 1998.
3. Lippincot. Microbiology by Lipponcott. William & Willkin, USA, 2001.
4. Alcamo. Introduction to Microbiology. John Bartlett Publishers, 6th Ed., 2003.
5. Collin and Lynes, Microbiological Methods, Vutterworth Heineman, Oxford, 1995.
6. M Mekallee, Microbiology: Essentials and Application, McGraw-Hill Inc, 2nd Ed.
7. Singleton and Sainsbury, Dictionary of Microbiology and Molecular biology, John Willey & Sons, New York, 2000.
8. Pelczar, Microbiology, McGraw-Hill Inc, 1996.
9. Prescott, Harley, Microbiology, 2nd Ed., Klein Wm C Brown Publishers, 2001.
Second Professional, First semester, Pharmacognosy
PHARMACOGNOSY-I
Drugs. Evaluation of Crude Drugs I E. Organoleptic, Microscopic, Physical, Chemical and Biological.
2. THE STUDY OF THE CRUDE DRUGS BELONGING TO VARIOUS FAMILIES OF MEDICINAL IMPORTANCE
Families Crude Drugs
a. Ranunculanceae Aconitum, Larkspur, Pulsatilla, Hydrastis.
b. Papaveraaceae Papaver Somniferum, Sanguinaria, Canadensis.
c. Leguminosae Acacia, Glycyrrhiza, Senna, Cassia, Tamarind.
d. Umbelliferae Fennel, Carum, Coriander, Conium, Asafoetida.
e. Apocynaceae Rauwolfia, Catharanthus.
f. Solanaceae Belladonna, Hycscyamus, Stramonium Capsicum.
g. Scrophulariaceae Digitalis, Verbascum (Mullien).
h. Labiatae Peppermint, Thyme, Spearmint, Salvia, Ocimum.
i. Liliaceae Garlic, Colchicum, Aloe.
j. Zingiberaceae Ginger, Curcuma.
3. GROWTH REGULATORS: General account with special reference to Auxins, Gibberellins Abscisic acid, Cytokinins and Ethylene.
PHARMACOGNOSY -I
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Introduction of the entire and broken parts of the plant drugs (Macro and organoleptic characters).
(Note: A minimum of 10 practicals will be conducted)
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed., Lea and Febiger, Philadelphia, 1988.
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto, 2002.
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission Monograph Series, Islamabad, pp74, 1985.
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission, Islamabad, 1985.
8. Youngkin H W, Text Book of Pharmacognosy, The Blakiston Co, Toronto, 6th Ed., 1948.
(Theory)
Cr. Hr. 03
Cr. Hr. 03
1. GENERAL INTRODUCTION: Historical Development and Scope of Pharmacognosy. Traditional system of Medicine/medicinal plants. Evolution of Modern system of Medicine (History of Modern System of Medicine). Classification of Crude Drugs with Special Emphasis to Chemical and Therapeutical System of Classification. Terminology Used in Pharmacognosy. Preparation of Crude Drugs for Commercial Market, Methods of Cultivation, Drying, Storage. Preservation, Packing, Deterioration and Adulteration of Crude
Drugs. Evaluation of Crude Drugs I E. Organoleptic, Microscopic, Physical, Chemical and Biological.
2. THE STUDY OF THE CRUDE DRUGS BELONGING TO VARIOUS FAMILIES OF MEDICINAL IMPORTANCE
Families Crude Drugs
a. Ranunculanceae Aconitum, Larkspur, Pulsatilla, Hydrastis.
b. Papaveraaceae Papaver Somniferum, Sanguinaria, Canadensis.
c. Leguminosae Acacia, Glycyrrhiza, Senna, Cassia, Tamarind.
d. Umbelliferae Fennel, Carum, Coriander, Conium, Asafoetida.
e. Apocynaceae Rauwolfia, Catharanthus.
f. Solanaceae Belladonna, Hycscyamus, Stramonium Capsicum.
g. Scrophulariaceae Digitalis, Verbascum (Mullien).
h. Labiatae Peppermint, Thyme, Spearmint, Salvia, Ocimum.
i. Liliaceae Garlic, Colchicum, Aloe.
j. Zingiberaceae Ginger, Curcuma.
3. GROWTH REGULATORS: General account with special reference to Auxins, Gibberellins Abscisic acid, Cytokinins and Ethylene.
PHARMACOGNOSY -I
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Introduction of the entire and broken parts of the plant drugs (Macro and organoleptic characters).
(Note: A minimum of 10 practicals will be conducted)
Recommended Books
1. V E Tyler, L R Brady and J E Robbers, Pharmacognosy, 9th Ed., Lea and Febiger, Philadelphia, 1988.
2. G E Trease and W C Evans, Pharmacognosy, W B Saunders, Philadelphia, Toronto, 2002.
3. K Usmanghani, Topics in Pharmacognosy, University Grants Commission Monograph Series, Islamabad, pp74, 1985.
4. T E Wellis, Text book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
5. Varro E Taylor, Pharmacognosy, Lee Febiger Philadelphia, 9th Ed.
6. Mohammad Ali, Introduction to Pharmacognosy, CBS Publishers & Distributors, New Delhi, 1986.
7. K Usmanghani, Chemical Pharmacognosy, University Grants Commission, Islamabad, 1985.
8. Youngkin H W, Text Book of Pharmacognosy, The Blakiston Co, Toronto, 6th Ed., 1948.
Second Professional, First semester, Pharmacology and Therapeutics
PHARMACOLOGY and THERAPEUTICS-I (General-I)
(Theory)
Cr. Hr. 03
1. GENERAL PHARMACOLOGY
(a) Introduction: History, Pharmacology and its classification and Drugs and their sources
(b) Routes of drugs administration: Advantages and disadvantages of Enteral Routes, Advantages and disadvantages of Parentral Routes and Advantages and disadvantages of Topical Routes.
(c) Pharmacokinetics: Drug solubility and passage of drugs across the body membranes, Plasma concentration of drugs and various factors affecting it (Absorption and factors influencing the rate of absorption (GIT and other routes) of drugs, Distribution and factors influencing the rate of distribution of drugs, Biotransformation and factors influencing the rate of biotransformation of drugs, Excretion, channels of excretion and factors influencing the rate of excretion of drugs), Definition of (Bioabvailability & Bioequivalence, Therapeutic Index, Plasma Half Life (t½), Dose-Response Curve, Area Under Curve, Volume of Distribution.
(d) Pharmacodynamics: Drug receptors and theories, Mechanisms of drug action, Specificity of drug action and Factors modifying the action & dosage of drugs.
2. DRUGS ACTING ON AUTONOMIC NERVOUS SYSTEM (ANS)
(a) Organization of ANS its subdivisions and innervations.
(b) Neurotransmitters in ANS, their synthesis, release and fate.
(c) Sympathetic agonist drugs: Catecholamines and Non-catecholamines.
(d) Sympathetic antagonist drugs: Adrenergics Nerve Blockers, Adrenoceptor antagonists (Alpha-adrenergic blockers and Betaadrenergic blockers).
(e) Parasympathetic (Cholinergic) agonists and Anticholinestrase inhibitors.
(f) Parasympathetic antagonists.
(g) Drugs acting on Ganglia (Ganglian stimulants and Ganglion blockers).
(h) Neuromuscular blocking drugs.
3. DRUGS ACTING ON GASTROINTESTINAL TRACT:
(a) Emetic.
(b) Anti-emetics.
(c) Purgatives: Bulk forming purgatives, Lubricant purgatives, Irritant purgatives and Saline Purgatives.
(d) Anti-diarrheal Agents.
(e) Treatment of Peptic & Dudenal Ulcers: Antiacids, H2-Receptor Antagonists, Antimuscarinic Agents, Proton Pump Inhibitors, Gastrin Receptor Antagonist and Cytoprotective agents.
(f) Drug treatment of chronic inflammatory diseases of bowel.
(g) Drugs affecting bile flow and Cholelithiasis.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY and; THERAPEUTICS-I (General-I)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Preparation of standard solution. Ringer solution. Tyrode solution. Kreb solution. Normal saline solution. To demonstrate the effects of sympathomimetic (Adrenaline) & sympatholytic drugs (Propranolol) on Frog’s heart. To demonstrate the effects of parasympathomimetic (Acetylcholine) and parasympatholytic (Atropine) drugs on Frog’s heart. To demonstrate the effects of an unknown drug on Frog’s heart. Routes of Administration of drugs.
(Note: A minimum of 10 practicals will be conducted)
Recommended Books
1. Goodman Gillman, Pharmacological basis of therapeutics. McGraw-Hill Book Company, New York, 1996.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology, Oxford University Press, New York, 1995.
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics, Popular Prakashan, Bomby, 1993.
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi, 4th Ed., 2000.
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung B G, Basic and Clinical Pharmacology, McGraw-Hill Medical Publishers, New York, 8th Ed., 2001
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001.
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993.
10. Qayum A, Fundamentals of Experimental Pharmacology. Ghandhara University, Peshawar.
11. Bertram G K, Basic and Clinical Pharmacology, Paramount Publishing Business & Professional Group, USA, 6th Ed., 1995.
12. William F, Ganong W F, Review of Medical physiology, Prentice Hall International Inc, New Jersey.
(Theory)
Cr. Hr. 03
1. GENERAL PHARMACOLOGY
(a) Introduction: History, Pharmacology and its classification and Drugs and their sources
(b) Routes of drugs administration: Advantages and disadvantages of Enteral Routes, Advantages and disadvantages of Parentral Routes and Advantages and disadvantages of Topical Routes.
(c) Pharmacokinetics: Drug solubility and passage of drugs across the body membranes, Plasma concentration of drugs and various factors affecting it (Absorption and factors influencing the rate of absorption (GIT and other routes) of drugs, Distribution and factors influencing the rate of distribution of drugs, Biotransformation and factors influencing the rate of biotransformation of drugs, Excretion, channels of excretion and factors influencing the rate of excretion of drugs), Definition of (Bioabvailability & Bioequivalence, Therapeutic Index, Plasma Half Life (t½), Dose-Response Curve, Area Under Curve, Volume of Distribution.
(d) Pharmacodynamics: Drug receptors and theories, Mechanisms of drug action, Specificity of drug action and Factors modifying the action & dosage of drugs.
2. DRUGS ACTING ON AUTONOMIC NERVOUS SYSTEM (ANS)
(a) Organization of ANS its subdivisions and innervations.
(b) Neurotransmitters in ANS, their synthesis, release and fate.
(c) Sympathetic agonist drugs: Catecholamines and Non-catecholamines.
(d) Sympathetic antagonist drugs: Adrenergics Nerve Blockers, Adrenoceptor antagonists (Alpha-adrenergic blockers and Betaadrenergic blockers).
(e) Parasympathetic (Cholinergic) agonists and Anticholinestrase inhibitors.
(f) Parasympathetic antagonists.
(g) Drugs acting on Ganglia (Ganglian stimulants and Ganglion blockers).
(h) Neuromuscular blocking drugs.
3. DRUGS ACTING ON GASTROINTESTINAL TRACT:
(a) Emetic.
(b) Anti-emetics.
(c) Purgatives: Bulk forming purgatives, Lubricant purgatives, Irritant purgatives and Saline Purgatives.
(d) Anti-diarrheal Agents.
(e) Treatment of Peptic & Dudenal Ulcers: Antiacids, H2-Receptor Antagonists, Antimuscarinic Agents, Proton Pump Inhibitors, Gastrin Receptor Antagonist and Cytoprotective agents.
(f) Drug treatment of chronic inflammatory diseases of bowel.
(g) Drugs affecting bile flow and Cholelithiasis.
Note:
1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group.
3. Newly introducted drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.
PHARMACOLOGY and; THERAPEUTICS-I (General-I)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Preparation of standard solution. Ringer solution. Tyrode solution. Kreb solution. Normal saline solution. To demonstrate the effects of sympathomimetic (Adrenaline) & sympatholytic drugs (Propranolol) on Frog’s heart. To demonstrate the effects of parasympathomimetic (Acetylcholine) and parasympatholytic (Atropine) drugs on Frog’s heart. To demonstrate the effects of an unknown drug on Frog’s heart. Routes of Administration of drugs.
(Note: A minimum of 10 practicals will be conducted)
Recommended Books
1. Goodman Gillman, Pharmacological basis of therapeutics. McGraw-Hill Book Company, New York, 1996.
2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.
3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology, Oxford University Press, New York, 1995.
4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics, Popular Prakashan, Bomby, 1993.
5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi, 4th Ed., 2000.
6. D R Laurance, Clinical Pharmacology, ELBS, London, 6th Ed., 1987.
7. Katzung B G, Basic and Clinical Pharmacology, McGraw-Hill Medical Publishers, New York, 8th Ed., 2001
8. Lipponcott, Pharmacology, Lippincot William & Willkin, USA, 2001.
9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993.
10. Qayum A, Fundamentals of Experimental Pharmacology. Ghandhara University, Peshawar.
11. Bertram G K, Basic and Clinical Pharmacology, Paramount Publishing Business & Professional Group, USA, 6th Ed., 1995.
12. William F, Ganong W F, Review of Medical physiology, Prentice Hall International Inc, New Jersey.
Second Professional, First semester, Pharmaceutics
PHARMACEUTICS-III (Pharmaceutical Preparations-I)
(Theory)
Cr. Hr. 03
1. Introduction: Dosage form. Ingredients
2. Pharmaceutical Calculations: Some Fundamentals of Measurements and Calculations. The Metric System. The Common Systems. Conversions. Calculation of Doses. Reducing and Enlarging Formulas. Density, Specific Gravity & Specific Volume. Weights and Volumes of Liquids. Percentage Preparations. Isotonic Solutions. HLB Values. Industrial Calculations. Some calculations involving Hydrogen-ion concentration.
3. Galenical Preparations: Infusions. Decoctions. Extracts. Fluid extracts Tinctures. Aromatic Waters.
4. Extraction Processes: Maceration: Purpose and process. Percolation: Purpose and Process. Liquid-Liquid extraction. Large scale extraction.
5. Solvents used in Pharmaceutical Preparations.
6. Oral Solutions, Syrups, Elixirs and Spirits: Solutions and their preparation, dry mixtures for solution, oral rehydrate solutions, oral colonic leverage solution. Syrup: components and preparation of Syrups. Elixirs: Preparation of elixirs, medicated and non-medicated elixirs.
7. Oral Suspensions, Emulsions, Magma and Gels: Preparations, Examples, and Importance.
PHARMACEUTICS-III (Pharmaceutical Preparations-I)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Prepartion of simple syrup, Orange syrup, Ferrous sulphate syrup, Cod Liver oil Emulsion, Liquid paraffin Emulsion, Throat paint (Mandle’s paint), Boroglycerine glycerite, Tannic acid glycerine, Spirit ammonia aromatic, Spirit of Ethyl nitrite. (A minimum of 10n practicals will be conducted)
Recommended Books
1. Michel E Aulton, Pharmaceutics, ELBS/Churchill Livingstone, London, 1998.
2. Bentley’s Book of Pharmaceutics, CBS Publishers & Distributors, New Delhi, 1986.
3. Pharmaceutics, the Science of Dosage Form Design. 2nd Ed., Haw Court Publisher, 2002.
4. E A Rawlins, Berdley’s Textbook of Pharmaceutics, edited by 8th (or recent edition) 1977. Macmillan Publishing Co Inc, New York.
5. Sprowl’s (Dittert L W, Eds.), American Pharmacy, 7th Ed, J B Lippincott Co, 1990.
(Theory)
Cr. Hr. 03
1. Introduction: Dosage form. Ingredients
2. Pharmaceutical Calculations: Some Fundamentals of Measurements and Calculations. The Metric System. The Common Systems. Conversions. Calculation of Doses. Reducing and Enlarging Formulas. Density, Specific Gravity & Specific Volume. Weights and Volumes of Liquids. Percentage Preparations. Isotonic Solutions. HLB Values. Industrial Calculations. Some calculations involving Hydrogen-ion concentration.
3. Galenical Preparations: Infusions. Decoctions. Extracts. Fluid extracts Tinctures. Aromatic Waters.
4. Extraction Processes: Maceration: Purpose and process. Percolation: Purpose and Process. Liquid-Liquid extraction. Large scale extraction.
5. Solvents used in Pharmaceutical Preparations.
6. Oral Solutions, Syrups, Elixirs and Spirits: Solutions and their preparation, dry mixtures for solution, oral rehydrate solutions, oral colonic leverage solution. Syrup: components and preparation of Syrups. Elixirs: Preparation of elixirs, medicated and non-medicated elixirs.
7. Oral Suspensions, Emulsions, Magma and Gels: Preparations, Examples, and Importance.
PHARMACEUTICS-III (Pharmaceutical Preparations-I)
(Laboratory)
Cr. Hr. 01
NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Prepartion of simple syrup, Orange syrup, Ferrous sulphate syrup, Cod Liver oil Emulsion, Liquid paraffin Emulsion, Throat paint (Mandle’s paint), Boroglycerine glycerite, Tannic acid glycerine, Spirit ammonia aromatic, Spirit of Ethyl nitrite. (A minimum of 10n practicals will be conducted)
Recommended Books
1. Michel E Aulton, Pharmaceutics, ELBS/Churchill Livingstone, London, 1998.
2. Bentley’s Book of Pharmaceutics, CBS Publishers & Distributors, New Delhi, 1986.
3. Pharmaceutics, the Science of Dosage Form Design. 2nd Ed., Haw Court Publisher, 2002.
4. E A Rawlins, Berdley’s Textbook of Pharmaceutics, edited by 8th (or recent edition) 1977. Macmillan Publishing Co Inc, New York.
5. Sprowl’s (Dittert L W, Eds.), American Pharmacy, 7th Ed, J B Lippincott Co, 1990.
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