Sunday, April 10, 2011

Oxicam derivatives

Action:

Meloxicam is relatively COX-2 selective.

Therapeutic uses:
(Similar to that of Acetic acid derivatives)

Pharmacokinetics:
These have usually longer half lives. Piroxicam and its metabolites are excreted in the urine whereas meloxicam and its metabolites are excreted equally in the urine and feces.

Adverse effects:
It may cause GI disturbances.

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