Friday, March 18, 2011

Diltiazem

It is similar in action to verapamil.


Actions:
It:
1. relieves spasm of coronary artery
2. causes a decrease in the AV conduction
3. causes a decrease in the firing time of the sinus node pacemaker
4. decrease heart rate
5. cause a depressed blood pressure

Therapeutic uses:
It is used for
1. variant angina.
2. Atrial fibrillation/flutter
3. Raynaud’s syndrome

Pharmacokinetics:
It undergoes hepatic metabolism.
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