Saturday, May 22, 2010

Some types of reactions in Pharmacy

Q: What do you mean by acetylation?
Ans: Acetylation is a reaction for the production of acetyl derivative.

Q: What do you mean by acetyl?
Ans: It is a radical showing CH3CO- in the formula. It is obtained from acetic acid (CH3COOH) by the removal of hydroxyl group (-OH).

Q: What is the use of acetylation and give its example?
Ans: Acetylation is used to lessen the toxicity of amines in drug production. Paracetamol is produced from p-nitrophenol by the use of acetylation.

Q: What do you mean by radical?

Ans: It represents a chemical group that works as a single unit in a chemical reaction.

Q: What do you know about alkylation?
Ans: It represents a chemical reaction in which the alkyl group is introduced into the compound in place of hydrogen.

Q: What do you mean by alkyl?
Ans: It is used to represent a hydrocarbon group obtained from alkane such as an ethyl (group).

Q: Give an example of alkylation.
Ans: Caffeine, an important constituent of coffee or tea, is obtained by the methylation (alkylation) of theophylline or theobromine.
Q: What do you mean by amination?
Ans: Amination represents the insertion of amine group into a compound.

Q: Give an example of amination.

Ans: Amphetamine is obtained from phenylacetone by the process of amination.
Q: What do you mean by condensation?
Ans: It represents the conversion of gas to a liquid or liquid to a solid. It also represents the bonding of molecules for the formation of denser substance and involves the connecting together of two or more organic molecules.

Q: Give an example of product obtained by condensation.
Ans: Hexylresorcinol is obtained by the condensation of resorcinol with hexanoic acid.

Q: What do you mean by esterification?
Ans: It represents the formation of ester.

Q: Give an example of esterification.
Ans: Formation of ethyl acetate by the reaction of ethanol and acetic acid.
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