These are the substances which are helpful in the coagulation of the blood.
Bleeding can be caused by
1. Fibrinolytic states arising after prostatectomy or gastrointestinal surgery.
In this case, hemophilia can be caused due to decrease of plasma coagulation factors such as factor VIII or IX.
Classification of Coagulants:
Protamine sulfate, Vitamin K, Aprotinin
Aminocaproic acid, Tranexamic acid