Sunday, April 24, 2011

Chlorothiazides

Chlorothiazed is the prototype of thiazide diuretics. This is used widely, orally effective and well tolerated.

They are effective in edema of hepatic cirrhosis and heart failure.

Pharmacokinetics:
Onset of action is 2 hours after oral administration and 10-15 minutes after IV administration. Its duration of action is about 4-12 hours.
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