Wednesday, March 2, 2011

Third Professional, Second Semester, Pharmaceutical Chemistry


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Note:- The topics will be taught with special reference to their Pharmaceutical Applications.

1. CHROMATOGRAPHIC METHODS: Column Chromatography, Thin Layer Chromatography, Gas Liquid Chromatography, HPLC and GCMS.

2. ELECTRO CHEMICAL METHODS: Potentiometry, Polarography and Radiochemical Techniques.



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NOTE:- Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the requirements, e.g. Determination of the Purity and Composition of the unknown drugs by using at least each of the above techniques.

Recommended Books

1. Lough W J, High Performance Liquid Chromatography, Blacki Academic Press, New York, 1996
2. William Kemp,Organic Spectroscopy, Ellsi Horwood, London, 1990. 3. M Aminuddin & Javed Iqbal, Theory and Practice of Chromatography, University Grants Commission, Islamabad-Pakistan (2000).
4. A H Beckett and J B Stennlake, Practical Pharmaceutical Chemistry, Part I and II, the aulton Press, London.
5. A M Knevel and F E Digangi, Jenkins’s quantitative Pharmaceutical Chemistry, McGraw-Hill Book Company, New York.
6. A Braithwaite and F J Smith, Chromatographic Methods, Chapman and Hall, London.
7. E Heftmann, Chromatography, Von Nostrond Reinheld Co, New York, 1975.
8. A Pryde and M J Gilbert, Applications of High Performance Liquid Chromatography, Chapman & Hall, London, 1979.
9. E Stahl, Thin Layer Chromatography, Springer-Verlag, Berlin, 1969.
10. R Hamilton, Introduction to HPLC, P A Sewell, Chapman & Hall, London, 1982.
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