Tuesday, March 22, 2011

Chlorthalidone

It is a thiazide like diuretic sulfonamide.

Action:
It causes inhibition of the transport of the sodium ions across the renal tubular epithelium in the ascending limb of the loop of Henle.

Pharmacokinetics:
It has long duration of action, so given once per day..

Uses:
It is used as a diuretic in the treatment of hypertension.
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